Molecular mechanism of tumorigenesis in transgenic mice carrying E1A and E1B genes of human adenovirus
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著者
書誌事項
- タイトル
-
Molecular mechanism of tumorigenesis in transgenic mice carrying E1A and E1B genes of human adenovirus
- 著者名
-
杉山, 文博
- 著者別名
-
スギヤマ, フミヒロ
- 学位授与大学
-
麻布大学
- 取得学位
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博士 (獣医学)
- 学位授与番号
-
乙第348号
- 学位授与年月日
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1995-06-07
注記・抄録
博士論文
目次
- 論文要旨 / (0001.jp2)
- TABLE OF CONTENTS / (0007.jp2)
- ABSTRACT / p1 (0009.jp2)
- INTRODUCTION / p5 (0013.jp2)
- MATERIALS AND METHODS / p7 (0015.jp2)
- 1.Construction of Fusion Transgene / p7 (0015.jp2)
- 2.Production of Transgenic Mice / p7 (0015.jp2)
- 3.Southern Blot Analysis / p8 (0016.jp2)
- 4.Chromosome Preparation and In Situ Hybridization / p8 (0016.jp2)
- 5.Histopathological Analysis / p9 (0017.jp2)
- 6.Northern Blot Analysis / p10 (0018.jp2)
- 7.Western Blot Analysis / p10 (0018.jp2)
- RESULTS / p12 (0020.jp2)
- 1.Production of transgenic mice carrying human renin promoter/E1A and E1B genes of human adenovirus type 12 / p12 (0020.jp2)
- 2.Carcinoid tumor in the transgenic mice carrying E1A and E1B genes of human adenovirus type 12 / p12 (0020.jp2)
- 3.Heritable formation of neuroectodermal tumor in the transgenic mice carrying E1A and E1B genes of human adenovirus type12 / p14 (0022.jp2)
- DISCUSSION / p18 (0026.jp2)
- REFERENCES / p27 (0035.jp2)
- TABLE / p37 (0045.jp2)
- FIGURES / p38 (0046.jp2)
- ACKNOWLEDGEMENTS / p52 (0060.jp2)
- SUMMARY IN JAPANESE / p53 (0061.jp2)
- ELECTRO BLOTTINGにおける泳動条件の影響 / (0071.jp2)
- ネコの生後間もない時期における血液変化 / p10 (0083.jp2)
- Isolation of Feline Plasma Hemopexin / (0089.jp2)
- Isolation of Feline Plasma Plasminogen / (0093.jp2)
- A CASE OF ASYMMETRIC FELINE CENTRAL RETINAL DEGENERATION* / (0097.jp2)
- Analysis of Feline Plasma Proteins by Immunoelectrophoresis and Polyacrylamide Gel Electrophoresis / (0103.jp2)
- Arched Isoelectric focusing Method for the Study of Proteins in the Cat Aqueous Humor* / p49 (0114.jp2)
- Purification,Electrophoretic Characterization and Plasma Concentrations of Feline or Canine Antithrombin III / (0121.jp2)
- Canine Fundus Abnormalities -A Survey of Over 29 Pound-Derived Breeds in Japan- / p31 (0129.jp2)
- Isolation and Observation of the Phenotype of Feline Fourth Component of Complement / p843 (0136.jp2)
- Spontaneous Leukemia Occurring in Aged Sic:Wistar Rats and its Transplantation into Rats / (0140.jp2)
- Species-Specific Induction of Angiotensinogen mRNA in Transgenic Mouse Liver during Acute Phase Reaction / p367 (0144.jp2)
- Species-Specific Kinetics of Mouse Renin Contribute to Maintenance of Normal Blood Pressure in Transgenic Mice with Overexpressed Human Angiotensinogen / (0147.jp2)
- Development of Mouse Oocytes Superovulated at Different Ages / p297 (0150.jp2)
- ｢9｣つくば高血圧マウス / (0152.jp2)
- トランスジェニック動物とレニン-アンジオテンシン系-つくば高血圧マウス作製の試み / p1406 (0157.jp2)
- 眼窩静脈叢採取血液と心臓採取血液の血液生化学値の比較-眼窩静脈叢採取血液での酵素値の上昇- / p99 (0165.jp2)
- Rat Renin Promoter Activity in Cultured Cells and Transgenic Mice / (0169.jp2)
- Chimeric Renin-Angiotensin System Demonstrates Sustained Increase in Blood Pressure of Transgenic Mice Carrying Both Human Renin and Human Angiotensinogen Genes* / p11617 (0174.jp2)
- Neurotropism of Mouse-adapted Haemagglutinating Encephalomyelitis Virus / (0179.jp2)
- Isolation of the Mouse Ren-1C Gene and Characterization of Renin Gene Expression in Both ES-D3 Cells and Their Parental Mouse Strain / (0186.jp2)
- Production of Transgenic Rats Using Pregnant and Pseudopregnant Rats Prepared at a Breeding Farm / p463 (0191.jp2)
- Comparative Study on Cross-Reaction of Leptospiral Antibodies in Several Serological Tests to Detect Antibodies to Borrelia burgdorferi in Dogs / (0195.jp2)
- Isolation of Salmonella from Impounded Dogs Introduced to a Laboratory / p119 (0198.jp2)
- Comparison of Plasma Endotoxin Levels in Germ-free,SPF and Conventional Laboratory Animals(Mice and Rats) / p89 (0201.jp2)
- Dependence of Angiotensin Production in Transgenic Mice Carrying either the Human Renin or Human Angiotensinogen Genes on Species-specific Kinetics of the Renin-Angiotensin System / (0205.jp2)
- 高血圧のモデル動物 / p148 (0209.jp2)
- レニン･アンジオテンシン系過剰発現マウス* / p163 (0216.jp2)
- トランスジェニックマウスとレニン-アンギオテンシン系 / p272 (0223.jp2)
- トランスジェニックバイオロジーへの招待 / p7 (0224.jp2)
- Angiotensinogen-deficient Mice with Hypotension* / p31334 (0229.jp2)
- Neuroectodermal Tumors Expressing c-,L-,and N-myc in Transgenic Mice That Carry the E1A/E1B Gene of Human Adenovirus Type 12* / p31252 (0233.jp2)
- Cortical expression of the human angiotensinogen gene in the kidney of transgenic mice / p1533 (0240.jp2)
- Species-Specific Expression of the Hepatic Renin Gene / (0243.jp2)