Synthesis of sulfur-containing triazole antifungal agents 硫黄原子を有するトリアゾール系抗真菌剤の合成研究

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Author

    • 宮内, 浩 ミヤウチ, ヒロシ

Bibliographic Information

Title

Synthesis of sulfur-containing triazole antifungal agents

Other Title

硫黄原子を有するトリアゾール系抗真菌剤の合成研究

Author

宮内, 浩

Author(Another name)

ミヤウチ, ヒロシ

University

北海道大学

Types of degree

博士 (理学)

Grant ID

乙第4897号

Degree year

1996-03-25

Note and Description

博士論文

Table of Contents

  1. CONTENTS / (0004.jp2)
  2. GENERAL INTRODUCTION / p1 (0006.jp2)
  3. SECTION1 SYNTHESIS OF TRIAZOLE ANTIFUNGAL AGENT SM-8668 AND ITS BIOLOGICALLY ACTIVE ENANTIOMER SM-9164 / p7 (0012.jp2)
  4. Chapter1-1 Diastereoselective Synthesis of dl-threo-2-(2,4-Difluorophenyl)-3-methylsulfonyl-1-(1H-1,2,4-triazol-1 -yl)-2-butanol(SM-8668) / p8 (0013.jp2)
  5. Chapter1-2 Optical Resolution of SM-8668: Preparation and Antifungal Activity of Enantiomers of SM-8668 / p15 (0020.jp2)
  6. Chapter1-3 Stereospecific Acetolysis of threo- and erythro-2-Aryl-2-[1-(methylthio)ethyl]oxiranes / p20 (0025.jp2)
  7. Chapter1-4 Optical Resolution of dl-threo-2-(2,4-Difluorophenyl)-2-[1-(methylthio)ethyl]oxirane. Its Application to Synthesis of SM-9164, a Biologically Active Enantiomer of SM-8668 / p28 (0033.jp2)
  8. Chapter1-5 Studies on Enantioselective Synthesis of SM-9164 / p36 (0041.jp2)
  9. SECTION2 SYNTHESIS AND THE STRUCTURE-ACTIVITY RELATIONSHIPS OF SULFUR-CONTAINING TRIAZOLE ANTIFUNGALS / p45 (0050.jp2)
  10. Chapter2-1 Synthesis and Antifungal Activity of Alkylthio and Alkylsulfonyl Derivatives of SM-8668 / p46 (0051.jp2)
  11. Chapter 2-2 Synthesis and Antifungal Activity of 3-Methyl and 3,3-Dimethyl Analogs of 2(2,4-Difluorophenyl)-3-(ω-substituted alkyl)sulfonyl-1-(1H-1,2,4-triazol-l-yl)-2-propanols / p54 (0059.jp2)
  12. SUMMARY AND GENERAL CONCLUSION / p65 (0070.jp2)
  13. EXPERIMENTAL / p69 (0074.jp2)
  14. REFERENCES / p160 (0165.jp2)
  15. ACKNOWLEDGMENT / p169 (0174.jp2)
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Codes

  • NII Article ID (NAID)
    500000132964
  • NII Author ID (NRID)
    • 8000000967540
  • DOI(NDL)
  • NDLBibID
    • 000000297278
  • Source
    • NDL ONLINE
    • NDL Digital Collections
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