Synthesis of rotenone analogues and their mode of action on NADH-ubiquinone oxidoreductases ロテノン類縁体の合成と種々のNADH-ユビキノン酸化還元酵素に対する作用機構
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Bibliographic Information
- Title
-
Synthesis of rotenone analogues and their mode of action on NADH-ubiquinone oxidoreductases
- Other Title
-
ロテノン類縁体の合成と種々のNADH-ユビキノン酸化還元酵素に対する作用機構
- Author
-
植野, 英樹
- Author(Another name)
-
ウエノ, ヒデキ
- University
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京都大学
- Types of degree
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博士 (農学)
- Grant ID
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甲第6521号
- Degree year
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1996-05-23
Note and Description
博士論文
Table of Contents
- 論文目録 / (0001.jp2)
- Contents / p1 (0003.jp2)
- General Introduction / p1 (0005.jp2)
- Chapter1:Comparison of the Inhibitory Action of Natural Rotenone and Its Stereoisomers with Various NADH-Ubiquinone Oxidoreductases / p3 (0006.jp2)
- 1-1 Introduction / p3 (0006.jp2)
- 1-2 Experimental Procedures / p5 (0007.jp2)
- 1-3 Results / p7 (0008.jp2)
- 1-4 Discussion / p14 (0012.jp2)
- 1-5 Conclusion / p18 (0014.jp2)
- Chapter2:Structural Factors of Rotenone Required for Inhibition of Various NADH-Ubiquinone Oxidoreductases / p19 (0014.jp2)
- 2-1 Introduction / p19 (0014.jp2)
- 2-2 Experimental Procedures / p20 (0015.jp2)
- 2-3 Results / p20 (0015.jp2)
- 2-4 Discussion / p26 (0018.jp2)
- 2-5 Conclusion / p29 (0019.jp2)
- Chapter3:Characterization of the Ubiquinone Catalytic Site in Mitochondrial NADH-Ubiquinone Oxidoreductase Based on Inhibitor Sensitivity / p31 (0020.jp2)
- 3-1 Introduction / p31 (0020.jp2)
- 3-2 Experimental Procedures / p32 (0021.jp2)
- 3-3 Results / p32 (0021.jp2)
- 3-4 Discussion / p41 (0025.jp2)
- 3-5 Conclusion / p44 (0027.jp2)
- Chapter4:Synthesis of Test Compounds / p47 (0028.jp2)
- 4-1 Synthesis of Rotenone Stereoisomers Used in Chapter1 / p47 (0028.jp2)
- 4-2 Synthesis of Rotenone Analogues Used in Chapters2 and 3 / p48 (0029.jp2)
- General Conclusion / p56 (0033.jp2)
- References / p58 (0034.jp2)
- Publication Lists / p63 (0036.jp2)
- Acknowledgements / p64 (0037.jp2)