Molecular design, chemical synthesis, and biological studies of enediyne compounds related to an antitumor antibiotic, dynemicin A 抗腫瘍性抗生物質ダイネミシンAに関連したエンジイン化合物の分子設計、化学合成、及び生物活性に関する研究
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著者
書誌事項
- タイトル
-
Molecular design, chemical synthesis, and biological studies of enediyne compounds related to an antitumor antibiotic, dynemicin A
- タイトル別名
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抗腫瘍性抗生物質ダイネミシンAに関連したエンジイン化合物の分子設計、化学合成、及び生物活性に関する研究
- 著者名
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海野, 良一
- 著者別名
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ウンノ, リョウイチ
- 学位授与大学
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名古屋大学
- 取得学位
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博士 (農学)
- 学位授与番号
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乙第5230号
- 学位授与年月日
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1997-05-29
注記・抄録
博士論文
目次
- Contents / p2 (0003.jp2)
- Acknowledgments / p3 (0004.jp2)
- Abbreviations / p4 (0005.jp2)
- Chapter1. Introduction and Background / p1 (0006.jp2)
- Chapter2. Synthesis and Biological Evaluation of Simple Dynemicin A Analogs Equipped with Triggering Devices / p18 (0023.jp2)
- Chapter3. Synthesis and Structure-Activity Relationships of 9-Acetoxy Enediyne Compounds Equipped with Aryl Carbamate Moieties / p29 (0034.jp2)
- Chapter4. Synthesis and Structure-Activity Relationships of 9-and 12-Substituted Enediyne Compounds Equipped with Aryl Carbamate Moieties / p40 (0045.jp2)
- Chapter5. Synthesis and Antitumor Activity of Water-Soluble Enediyne Compounds Equipped with Aryl Carbamate Moieties / p55 (0060.jp2)
- Chapter6. Summary / p63 (0068.jp2)
- Experimental Section / p70 (0075.jp2)
- For Chapter2 / p72 (0077.jp2)
- For Chapter3 / p81 (0086.jp2)
- For Chapter4 / p100 (0105.jp2)
- For Chapter5 / p115 (0120.jp2)
- 論文目録 / (0130.jp2)
- Reversed Effects between Crude and Processed Ginger Extracts on PGF₂α-Induced Contraction in Mouse Mesenteric Veins / p243 (0274.jp2)
- PROFILE OF A NEW ALDOSE REDUCTASE INHIBITOR,(2S,4S)-6-FLUORO-2',5'-DIOXOSPIRO-[CHROMAN-4,4'-IMIDAZOLIDINE]-2-CARBOXAMIDE(SNK-860) / p89 (0279.jp2)
- Synthesis and Aldose Reductase Inhibitory Activity of 2-Substituted-6-Fluoro-2,3-dihydrospiro[4H-1-benzopyran-4,4'-imidazolidine]-2',5'-diones / (0288.jp2)
- Synthesis and Aldose Reductase Inhibitory Activity of 2-Substituted 6-Fluoro-2,3-dihydrospiro[4H-1-benzopyran-4,4'-imidazolidine]-2',5'-diones / p1474 (0296.jp2)
- Synthesis and Biological Evaluation of Both Enantiomers of Dynemicin A Model Compound / p9339 (0303.jp2)