Studies on the improvement of the antigen affinity and specificity of human antibodies by light chain shifting 軽鎖交換によるヒト抗体の抗原親和性及び特異性の改良に関する研究
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Bibliographic Information
- Title
-
Studies on the improvement of the antigen affinity and specificity of human antibodies by light chain shifting
- Other Title
-
軽鎖交換によるヒト抗体の抗原親和性及び特異性の改良に関する研究
- Author
-
Siripen Thongpassano
- Author(Another name)
-
シリペン トーンパッサノ
- University
-
九州大学
- Types of degree
-
博士 (農学)
- Grant ID
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甲第4164号
- Degree year
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1997-09-22
Note and Description
博士論文
Table of Contents
- CONTENTS / p1 (0003.jp2)
- CHAPTER 1: GENERAL INTRODUCTION / p1 (0006.jp2)
- CHAPTER 2: SPECIFICITY OF ANTIBODIES FROM NEW LIGHT CHAIN PRODUCING HUMAN PLASMA B CELL / p8 (0013.jp2)
- 1.Introduction / p8 (0013.jp2)
- 2.Materials and methods / p9 (0014.jp2)
- 3.Results / p11 (0016.jp2)
- 4.Discussion and conclusion / p13 (0018.jp2)
- CHAPTER 3: ALTERED REACTIVITY OF ANTIBODY DERIVED FROM CONCANAVALIN A-RESISTANT HYBRIDOMA CELLS BY INTRODUCTION OF DRUG RESISTANT GENE / p19 (0024.jp2)
- 1.Introduction / p19 (0024.jp2)
- 2.Materials and methods / p21 (0026.jp2)
- 3.Results / p22 (0027.jp2)
- 4.Discussion and conclusion / p25 (0030.jp2)
- CHAPTER 4: GENERATION OF HIGH AFFINITY AND SPECIFICITY ANTIBODY FROM HUMAN PLASMA CELL BY LIGHT CHAIN SHIFTING / p32 (0037.jp2)
- 1.Introduction / p32 (0037.jp2)
- 2.Materials and methods / p33 (0038.jp2)
- 3.Results / p35 (0040.jp2)
- 4.Discussion and conclusion / p40 (0045.jp2)
- CHAPTER 5: ACQUIRED AUTOANTIBODIES FROM HUMAN PLASMA CELLS BY LIGHT CHAIN SHIFTING / p50 (0055.jp2)
- 1.Introduction / p50 (0055.jp2)
- 2.Materials and methods / p51 (0056.jp2)
- 3.Results / p52 (0057.jp2)
- 4.Discussion and conclusion / p55 (0060.jp2)
- CHAPTER 6: GENERAL DISCUSSION AND CONCLUSION / p66 (0071.jp2)
- ACKNOWLEDGMENTS / p73 (0078.jp2)
- REFERENCES / p74 (0079.jp2)
