Thermosensitive magnetoliposomes as a new drug carrier and their fundamental characteristics 新しい薬物担体としての温度・磁気感受性リポソームとその基礎的性質

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Title: Thermosensitive magnetoliposomes as a new drug carrier and their fundamental characteristics

博士論文

TABLE OF CONTENTS / p9 (0010.jp2)
Acknowledgment / p2 (0003.jp2)
Abstract / p4 (0005.jp2)
List of Illustrations / p11 (0012.jp2)
List of Tables / p18 (0019.jp2)
List of Abbreviations / p19 (0020.jp2)
General Introduction1 / p1 (0022.jp2)
Chapter I Preparation and Characterization of Thermosensitive Magnetoliposomes: an On-Line Flow System for Quantifying Magnetic Responsiveness / p4 (0025.jp2)
A.Introduction / p5 (0026.jp2)
B.Materials and Methods / p6 (0027.jp2)
C.Results / p12 (0033.jp2)
D.Discussion / p24 (0045.jp2)
Chapter II Magnetic Targeting of Thermosensitive Magnetoliposomes to Mouse Livers in an In Situ On-Line Perfusion System / p28 (0049.jp2)
A.Introduction / p29 (0050.jp2)
B.Materials and Methods / p30 (0051.jp2)
C.Results / p38 (0059.jp2)
D.Discussion / p42 (0063.jp2)
Chapter III Release of 5-Fluorouracil from Thermosensitive Magnetoliposomes Induced by an Electromagnetic Field / p49 (0070.jp2)
A.Introduction / p50 (0071.jp2)
B.Materials and Methods / p51 (0072.jp2)
C.Results / p56 (0077.jp2)
D.Discussion / p61 (0082.jp2)
Chapter IV Microdialysis Assessment of 5-Fluorouracil Release from Thermosensitive Magnetoliposomes Induced by an Electromagnetic Field in Tumor-Bearing Mice / p66 (0087.jp2)
A.Introduction / p67 (0088.jp2)
B.Materials and Methods / p68 (0089.jp2)
C.Results / p76 (0097.jp2)
D.Discussion / p82 (0103.jp2)
Conclusions and Perspectives / p86 (0107.jp2)
Appendix / p89 (0110.jp2)
References / p90 (0111.jp2)

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