EEG dipole localization in human cerebral cortex : use of computer simulation to measure changes in the neuropathology of alzheimer's disease アルツハイマー型痴呆による大脳皮質構造の変化が双極子度に与える影響とアルツハイマー型痴呆診断への応用
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著者
書誌事項
- タイトル
-
EEG dipole localization in human cerebral cortex : use of computer simulation to measure changes in the neuropathology of alzheimer's disease
- タイトル別名
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アルツハイマー型痴呆による大脳皮質構造の変化が双極子度に与える影響とアルツハイマー型痴呆診断への応用
- 著者名
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原, 淳子
- 著者別名
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ハラ, ジュンコ
- 学位授与大学
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慶応義塾大学
- 取得学位
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博士(学術)
- 学位授与番号
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甲第1703号
- 学位授与年月日
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1999-03-23
注記・抄録
博士論文
目次
- 論文目録 / (0001.jp2)
- Contents / p1 (0006.jp2)
- INTRODUCTION / p5 (0010.jp2)
- CHAPTER1:ALZHEIMER'S DISEASE / p7 (0012.jp2)
- 1.1 NEUROPATHOLOGICAL CHANGES OF AD / p7 (0012.jp2)
- 1.2 CLINICAL DIAGNOSIS OF AD / p10 (0015.jp2)
- 1.3 ELECTROPHYSIOLOGICAL STUDIES OF AD AND OTHER DEMETING DISORDERS / p12 (0017.jp2)
- 1.4 CLINICALLY RELEVANT AREAS FOR FUTURE ELECTROPHYSIOLOGICAL RESEARCH / p13 (0018.jp2)
- CHAPTER2:NEUROBIOLOGY OF THE ELECTROENCEPHALOGRAM(EEG) / p15 (0020.jp2)
- 2.1 NEURONS AND SYNAPSES / p15 (0020.jp2)
- 2.2 ELECTRIC PROPERTIES OF NEURONS / p17 (0022.jp2)
- 2.3 GENERATION OF EEG / p20 (0025.jp2)
- 2.4 ELECTROENCEPHALOGRAPHY,EVOKED POTENTIALS AND EVENT RELATED POTENTIALS / p22 (0027.jp2)
- CHAPTER3:DIPOLE SOURCE LOCALIZATION / p25 (0030.jp2)
- 3.1 NEURONALACTIVITY AND ELECTRIC DIPOLE / p25 (0030.jp2)
- 3.2 DIPOLE SOURCE LOCALIZATION METHOD / p25 (0030.jp2)
- 3.3 ACCURACY AND RELIABILITY / p27 (0032.jp2)
- 3.4 APPLICATION OF DIPOLE SOURCE LOCALIZATION / p27 (0032.jp2)
- CHAPTER4:COMPUTER SIMULATIONS TO CONSTRAIN DIAGNOSTIC INTERPRETATION / p29 (0034.jp2)
- 4.1 ALZHEIMER'S DISEASE AND COMPUTER SIMULATION STUDIES / p29 (0034.jp2)
- 4.2 COMPUTER SIMULATION USING REALISTIC CORTICAL AND HEAD SHAPE MODEL / p30 (0035.jp2)
- 4.3 SYSTEMATIC ANALYSIS OF GOODNESS-OF-FIT / p34 (0039.jp2)
- 4.4 SUMMARY:ALZHEIMER'S DISEASE AND RANDOMLY ORIENTED DIPOLES / p41 (0046.jp2)
- CHAPTER5:CLINICAL EXPERIMENTS TO DIFFERENTIALLY DIAGNOSE DEMENTIA / p45 (0050.jp2)
- 5.1 METHODS / p45 (0050.jp2)
- 5.2 GOODNESS-OF-FIT AND SEVERITY OF AD / p47 (0052.jp2)
- 5.3 GOODNESS-OF-FIT AND VASCULAR DEMENTIA / p50 (0055.jp2)
- 5.4 GOODNESS-OF-FIT AND OTHER DISORDERS / p51 (0056.jp2)
- 5.5 GOODNESS-OF-FIT AND AGE-MATCHED CONTROL / p52 (0057.jp2)
- 5.6 WHY IS GOODNESS-OF-FIT LOWER IN AD? / p52 (0057.jp2)
- CHAPTER6:MONITORING PROGRESSION OF ALZHEIMER'S DISEASE / p57 (0062.jp2)
- 6.1 METHODS / p57 (0062.jp2)
- 6.2 GOODNESS-OF-FIT CHANGES / p60 (0065.jp2)
- 6.3 OTHER MEASUREMENT / p62 (0067.jp2)
- 6.3 SUMMARY / p67 (0072.jp2)
- CHAPTER7:CONCLUDING REMARKS:EEG AS DIAGNOSTIC TOOL FOR ALZHEIMER'S DISEASE / p68 (0073.jp2)
- ACKNOWLEDGEMENTS / p70 (0075.jp2)
- REFERENCE / p71 (0076.jp2)
- APPENDIX1:CEREBRAL CORTEX / p79 (0084.jp2)
- APPENDIX2:CLINICAL DEMENTIA SCALE / p83 (0088.jp2)
- APPENDIX3:GOODNESS-OF-FIT DIFFERENCE FOR DIFFERENT MODEL / p87 (0092.jp2)
- APPENDIX4:TRANSFER MATRIX / p89 (0094.jp2)
- APPENDIX5:SIMPLEX METHOD / p90 (0095.jp2)