Effects of hypertension-related gene polymorphisms and lifestyle factors on blood pressure 高血圧関連遺伝子多型と血圧および生活習慣の関連
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著者
書誌事項
- タイトル
-
Effects of hypertension-related gene polymorphisms and lifestyle factors on blood pressure
- タイトル別名
-
高血圧関連遺伝子多型と血圧および生活習慣の関連
- 著者名
-
張, 英寧
- 著者別名
-
チョウ, エイネイ
- 学位授与大学
-
山梨医科大学
- 取得学位
-
博士(医学)
- 学位授与番号
-
甲第182号
- 学位授与年月日
-
1999-03-24
注記・抄録
博士論文
目次
- Contents / (0002.jp2)
- 1.Abstract / p1 (0004.jp2)
- 2.Introduction / p3 (0006.jp2)
- 2.1 Renin-angiotensin system(RAS) / p3 (0006.jp2)
- 2.2 Angiotensinogen(AGT) / p4 (0007.jp2)
- 2.3 Angiotensin-converting enzyme(ACE) / p5 (0008.jp2)
- 2.4 α-Adducin(AAD) / p5 (0008.jp2)
- 2.5 Hypertension and RAS / p6 (0009.jp2)
- 2.6 The aims of the present study / p8 (0011.jp2)
- 3.Methods / p10 (0013.jp2)
- 3.1 Subjects / p10 (0013.jp2)
- 3.2 Extraction of genetic DNA / p10 (0013.jp2)
- 3.3 Genetic analyses / p10 (0013.jp2)
- 3.5 Lifestyle questionnaire / p13 (0016.jp2)
- 3.6 Statistical analysis / p13 (0016.jp2)
- 4.Results / p14 (0017.jp2)
- 4.1 Clinical characteristics of the study population / p15 (0018.jp2)
- 4.2 Differences between allele frequency of the three gene polymorphisms among different ethnic groups / p15 (0018.jp2)
- 4.3 Distribution of allele and genotype frequencies for the three gene polymorphisms / p16 (0019.jp2)
- 4.4 Genotypes groups and their blood pressure changes during the period of 1994 to 1998 / p16 (0019.jp2)
- 4.5 Correlation analysis of differences among the three gene polymorphisms and factors related to blood pressure changes / p17 (0020.jp2)
- 4.6 Multiple regression analysis of gene polymorphisms,and related factors and blood pressure / p17 (0020.jp2)
- 5.Discussion / p19 (0022.jp2)
- 5.1 Effect of AGT M235T gene polymorphism on blood pressure / p19 (0022.jp2)
- 5.2 Effect of ACE I/D gene polymorphism on blood pressure / p19 (0023.jp2)
- 5.3 Effect of AAD G460T gene polymorphism on blood pressure / p22 (0025.jp2)
- 5.4 Effects of lifestyle factors on the three gene polymorphisms and blood pressure / p23 (0026.jp2)
- 6.Acknowledgment / p26 (0029.jp2)
- 7.References / p27 (0030.jp2)
- 8.Tables and Figures / (0037.jp2)