Crystal structure of human RhoA complexed with a GTP analogue 活性型ヒトRhoA-GTPアナログ複合体の結晶構造
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Bibliographic Information
- Title
-
Crystal structure of human RhoA complexed with a GTP analogue
- Other Title
-
活性型ヒトRhoA-GTPアナログ複合体の結晶構造
- Author
-
伊原, 健太郎
- Author(Another name)
-
イハラ, ケンタロウ
- University
-
奈良先端科学技術大学院大学
- Types of degree
-
博士(バイオサイエンス)
- Grant ID
-
甲第66号
- Degree year
-
1999-03-24
Note and Description
博士論文
Table of Contents
- 博士論文要旨 / (0003.jp2)
- Contents / p2 (0005.jp2)
- Introduction / p3 (0006.jp2)
- Materials and methods / p10 (0013.jp2)
- Preparation and crystallization of [化学式] / p10 (0013.jp2)
- Data collection and structure determination / p11 (0014.jp2)
- Structure refinement / p12 (0015.jp2)
- Results / p24 (0027.jp2)
- Overall structure / p24 (0027.jp2)
- Insertion regions / p25 (0028.jp2)
- Phosphate-binding loop / p27 (0030.jp2)
- Switch I / p27 (0030.jp2)
- Strand B2 and B3 / p28 (0031.jp2)
- Switch II / p29 (0032.jp2)
- Magnesium ion binding / p30 (0033.jp2)
- Guanosine nucleotide binding / p30 (0033.jp2)
- Triphosphate binding / p31 (0034.jp2)
- Putative nucleophilic water molecule / p32 (0035.jp2)
- Discussion / p48 (0051.jp2)
- Modification sites by bacterial toxins / p48 (0051.jp2)
- GTP/GDP switching and effector binding / p50 (0053.jp2)
- GEF and GDS binding / p52 (0055.jp2)
- GDI binding / p53 (0056.jp2)
- Effects of the γ-sulfur atom and the G14V mutation on the GTPase activity / p53 (0056.jp2)
- Conclusion / p61 (0064.jp2)
- Acknowledgements / p62 (0065.jp2)
- References / p63 (0066.jp2)
