Conformational diversity and local dynamics of biologically active peptides as studied by solid-state NMR 固体高分解能NMRによる生理活性ペプチドの高次構造と局所ダイナミクスに関する研究

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著者

    • 上平, 美弥 カミヒラ, ミヤ

書誌事項

タイトル

Conformational diversity and local dynamics of biologically active peptides as studied by solid-state NMR

タイトル別名

固体高分解能NMRによる生理活性ペプチドの高次構造と局所ダイナミクスに関する研究

著者名

上平, 美弥

著者別名

カミヒラ, ミヤ

学位授与大学

姫路工業大学

取得学位

博士 (理学)

学位授与番号

甲第78号

学位授与年月日

2000-03-24

注記・抄録

博士論文

目次

  1. CONTENTS / p1 (0003.jp2)
  2. GENERAL INTRODUCTION / p1 (0006.jp2)
  3. PART I:Conformational Diversity and Dynamics of Enkephalins in Crystalline States / (0009.jp2)
  4. Chapter1:Distinction of Polymorphs, Backbone Dynamics, and Local Conformational Rearrangements of Enkephalins Induced by Dehydration or Freezing of Motions of Bound Solvent Molecules / p8 (0010.jp2)
  5. 1.1.Introduction / p8 (0010.jp2)
  6. 1.2.Experimental Section / p10 (0011.jp2)
  7. 1.3.Results / p12 (0012.jp2)
  8. 1.4.Discussion / p37 (0024.jp2)
  9. 1.5 Conclusion / p44 (0028.jp2)
  10. Chapter2:Phenyl Ring Dynamics of Enkephalin Molecules and Behavior of Bound Solvents / p45 (0028.jp2)
  11. 2.1.Introduction / p45 (0028.jp2)
  12. 2.2.Experimental Section / p47 (0029.jp2)
  13. 2.3.Results / p48 (0030.jp2)
  14. 2.4.Discussion / p64 (0038.jp2)
  15. 2.5.Conclusion / p73 (0042.jp2)
  16. References / p74 (0043.jp2)
  17. PART Ⅱ:Fibrillation Mechanism of Human Calcitonin / p79 (0045.jp2)
  18. Chapter1:Conformational Transitions and Fibrillation Mechanism of Human Calcitonin / p80 (0046.jp2)
  19. 1.1.Introduction / p80 (0046.jp2)
  20. 1.2.Experimental Section / p84 (0048.jp2)
  21. 1.3.Results / p87 (0049.jp2)
  22. 1.4.Discussion / p106 (0059.jp2)
  23. 1.5.Conclusion / p119 (0065.jp2)
  24. Chapter2:Effect of Electrostatic Interaction on Fibril Formation of Human Calcitonin / p121 (0066.jp2)
  25. 2.1.Introduction / p121 (0066.jp2)
  26. 2.2.Experimental Section / p123 (0067.jp2)
  27. 2.3.Results / p125 (0068.jp2)
  28. 2.4.Discussion / p143 (0077.jp2)
  29. 2.5 Conclusion / p150 (0081.jp2)
  30. References / p152 (0082.jp2)
  31. PART Ⅲ:Conformation and Dynamics of Substrate-Related Peptide Bound to Papain / p156 (0084.jp2)
  32. Chapter 1:Interaction between Papain and Substrate-Related Peptide in The Solution and Solid States / p157 (0084.jp2)
  33. 1.1.Introduction / p157 (0084.jp2)
  34. 1.2.Experimental Section / p160 (0086.jp2)
  35. 1.3.Results / p162 (0087.jp2)
  36. 1.4.Discussion / p169 (0090.jp2)
  37. 1.5.Conclusion / p177 (0094.jp2)
  38. Chapter2:Conformation and Dynamics of Substrate-Related Peptide Bound to Papain in the Crystalline State / p179 (0095.jp2)
  39. 2.1.Introduction / p179 (0095.jp2)
  40. 2.2.Experimental Section / p180 (0096.jp2)
  41. 2.3.Results / p181 (0096.jp2)
  42. 2.4.Discussion / p193 (0102.jp2)
  43. 2.5.Conclusion / p198 (0105.jp2)
  44. references / p199 (0105.jp2)
  45. SUMMARY AND GENERAL CONCLUSION / p203 (0107.jp2)
  46. ACKNOWLEGDEMENT / p208 (0110.jp2)
  47. LIST OF PUBLICATIONS / p209 (0110.jp2)
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各種コード

  • NII論文ID(NAID)
    500000186821
  • NII著者ID(NRID)
    • 8000000187104
  • DOI(NDL)
  • NDL書誌ID
    • 000000351135
  • データ提供元
    • NDL ONLINE
    • NDLデジタルコレクション
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