The membrane destabilizing activity and the critical glycine residue of the influenza virus hemagglutinin fusion peptide-based synthetic peptide

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タイトル: The membrane destabilizing activity and the critical glycine residue of the influenza virus hemagglutinin fusion peptide-based synthetic peptide

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論文目録 / (0001.jp2)
Contents / p5 (0008.jp2)
Abstract / p1 (0004.jp2)
Abbreviations and Acronyms / p3 (0006.jp2)
Contents / p5 (0008.jp2)
1. Introduction / p7 (0010.jp2)
1.1. Membrane Fusion / p7 (0010.jp2)
1.2. Influenza Virus Hemagglutinin / p9 (0012.jp2)
1.3. The Fusion Peptide / p19 (0022.jp2)
1.4. The Scope of This Research / p25 (0028.jp2)
2. Materials and Methods / p28 (0031.jp2)
2.1. Peptide Nomenclature / p28 (0031.jp2)
2.2. Peptide Synthesis / p28 (0031.jp2)
2.3. Amino Acid Analysis / p31 (0034.jp2)
2.4. Preparation of Liposomes / p32 (0035.jp2)
2.5. Lipid Mixing / p33 (0036.jp2)
2.6. Aqueous Content Mixing / p34 (0037.jp2)
2.7. Aqueous Content Leakage / p35 (0038.jp2)
2.8. Spectroscopic Experiments / p36 (0039.jp2)
3. Results / p38 (0041.jp2)
3.1. Peptide Synthesis / p38 (0041.jp2)
3.2. Preliminary Lipid Mixing Assay / p39 (0042.jp2)
3.3. Membrane Fusion Assay for Peptide III / p41 (0044.jp2)
3.4. LUV Leakage Assay / p41 (0044.jp2)
3.5. CD and Fluorescence Spectra / p42 (0045.jp2)
4. Discussion / p44 (0047.jp2)
4.1. Activity of Peptide III / p44 (0047.jp2)
4.2. Substitutions to Change the Bulkiness of the Side Chains / p45 (0048.jp2)
4.3. Glycine in the Middle Part of the Peptide / p49 (0052.jp2)
4.4. Conclusions / p52 (0055.jp2)
Acknowledgements / p53 (0056.jp2)
References / p54 (0057.jp2)
Tables and Figures / p66 (0069.jp2)
The relationship between the behavior of the α-helical peptide in phospholipid bilayer and its fusion activity / (0106.jp2)