Human hemoglobin vesicles and establishment of their surface modification method ヒトヘモグロビン小胞体とその表面修復法の確立

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著者

    • 宗, 慶太郎 ソウ, ケイタロウ

書誌事項

タイトル

Human hemoglobin vesicles and establishment of their surface modification method

タイトル別名

ヒトヘモグロビン小胞体とその表面修復法の確立

著者名

宗, 慶太郎

著者別名

ソウ, ケイタロウ

学位授与大学

早稲田大学

取得学位

博士 (工学)

学位授与番号

甲第1412号

学位授与年月日

2000-03-15

注記・抄録

博士論文

目次

  1. Table of Contents / p1 (0004.jp2)
  2. Preface / (0003.jp2)
  3. Chapter1:Intermolecular Interaction and Hemoglobin Vesicles / p1 (0007.jp2)
  4. 1.Introduction / p1 (0007.jp2)
  5. 2.Intermolecular Interaction and Molecular Assemble / p1 (0007.jp2)
  6. 3.Assembly of the Amphiphile / p6 (0010.jp2)
  7. 4.Physicochemical Properties of Phospholipid Vesicles / p11 (0012.jp2)
  8. 5.Hemoglobin Vesicles and Red Blood Cells / p17 (0015.jp2)
  9. 6.Surface Modification of the Phospholipid Vesicles / p21 (0017.jp2)
  10. References and Notes / p25 (0019.jp2)
  11. Chapter2:Properties and Molecular Assemblies of Glycolipids / p27 (0020.jp2)
  12. 1.Introduction / p27 (0020.jp2)
  13. 2.Synthesis of the Glycolipids / p28 (0021.jp2)
  14. 3.Structure of the glycolipids and their molecular assemblies / p33 (0023.jp2)
  15. 4.Control the assemblies by the preparation method / p39 (0026.jp2)
  16. 5.Analysis of the assembling structure by using the molecular dynamic simulation / p44 (0029.jp2)
  17. 6.Thermodynamical analysis of glycolipid assemblies complexed with concanavalin A / p48 (0031.jp2)
  18. 7.Summary / p50 (0032.jp2)
  19. References and Notes / p51 (0032.jp2)
  20. Chapter3:Surface Modification of the Vesicles with Synthetic Glycolipid / p53 (0033.jp2)
  21. 1.Introduction / p53 (0033.jp2)
  22. 2.Surface-modified vesicles with glycolipids / p54 (0034.jp2)
  23. 3.Stability of the Glyco-vesicles / p55 (0034.jp2)
  24. 4.Vesicle aggregation by addition of water-soluble polymer / p57 (0035.jp2)
  25. 5.Aggregation of the vesicles by interaction between saccharide chains and water-soluble polymers / p59 (0036.jp2)
  26. 6.Vesicle aggregation triggered by interaction between water-soluble polymer and glycolipid / p64 (0039.jp2)
  27. References and Notes / p68 (0041.jp2)
  28. Chapter4:Surface Modification of Vesicles with Polyoxyethylene-lipids / p70 (0042.jp2)
  29. 1.Introduction / p70 (0042.jp2)
  30. 2.POE-modified vesicles / p70 (0042.jp2)
  31. 3.Surface modification of the phospholipid vesicles by using the co-assembling phenomenon / p73 (0043.jp2)
  32. 4.Physicochemical parameters of co-assemble / p78 (0046.jp2)
  33. 5.Relationship between stability of the vesicles and degree of the POE-modification / p86 (0050.jp2)
  34. 6.Interbilayer transfer of POE-lipid / p89 (0051.jp2)
  35. 7.Summary / p92 (0053.jp2)
  36. References and Notes / p93 (0053.jp2)
  37. Chapter5:Hydrophobic-Hydrophilic Balance of Multi-acyl lipids and their Intermolecular Interaction / p95 (0054.jp2)
  38. 1.Introduction / p95 (0054.jp2)
  39. 2.Syhthesis of the amphiphile with multi-acyl chains / p95 (0054.jp2)
  40. 3.Relationship between hydrophilic-hydrophobic balance and intermolecular interaction force / p104 (0059.jp2)
  41. 4.Co-assemmble with phospholipid vesicles / p110 (0062.jp2)
  42. 5.Summary / p112 (0063.jp2)
  43. References and Notes / p114 (0064.jp2)
  44. Chapter6 Stability of the Surface-modified Hemoglobin Vesicles / p116 (0065.jp2)
  45. 1.Introduction / p116 (0065.jp2)
  46. 2.Preparation of HbV / p116 (0065.jp2)
  47. 3.Surface modification of HbV / p118 (0066.jp2)
  48. 4.Rheological properties / p120 (0067.jp2)
  49. 5.Stability in long-term storage / p123 (0068.jp2)
  50. 6.The effect of POE-modification in vivo / p136 (0075.jp2)
  51. 7.Summary / p138 (0076.jp2)
  52. References and Notes / p139 (0076.jp2)
  53. Chapter7 Future Aspect of the Surface-modified Hemoglobin Vesicles as an Oxygen Infusion / p141 (0077.jp2)
  54. 1.Oxygen Infusion / p141 (0077.jp2)
  55. 2.Stability of hemoglobin vesicles / p142 (0078.jp2)
  56. 3.Hemoglobin / p143 (0078.jp2)
  57. 4.Other application / p144 (0079.jp2)
  58. References and Notes / p145 (0079.jp2)
  59. List of Publication / (0080.jp2)
  60. Acknowledgement / (0080.jp2)
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各種コード

  • NII論文ID(NAID)
    500000188465
  • NII著者ID(NRID)
    • 8000000188748
  • DOI(NDL)
  • NDL書誌ID
    • 000000352779
  • データ提供元
    • NDL ONLINE
    • NDLデジタルコレクション
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