Study on drug-DNA minor groove interactions and DNA supercoiling by using hydrostatic pressure as a perturbation agent

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著者

    • 唐, 国慶 トウ, コクケイ

書誌事項

タイトル

Study on drug-DNA minor groove interactions and DNA supercoiling by using hydrostatic pressure as a perturbation agent

著者名

唐, 国慶

著者別名

トウ, コクケイ

学位授与大学

京都工芸繊維大学

取得学位

博士 (学術)

学位授与番号

甲第187号

学位授与年月日

1999-03-25

注記・抄録

博士論文

目次

  1. Content / (0003.jp2)
  2. Chapter1:General Introduction / p1 (0004.jp2)
  3. §1.1 The Minor groove Binding of drugs with DNA / p1 (0004.jp2)
  4. §1.2 DNA Supercoiling / p4 (0006.jp2)
  5. §1.3 High pressure study related to structure and drug-interactions of nucleic acids / p7 (0007.jp2)
  6. §1.4 Scope of present work / p8 (0008.jp2)
  7. References / p10 (0009.jp2)
  8. Chapter2:DNA Minor Groove Binding Studied by Restriction Endonuclease Protection Assay under Hydrostatic Pressure / p12 (0010.jp2)
  9. §2.1 Introduction / p12 (0010.jp2)
  10. §2.2 Materials and Methods / p13 (0010.jp2)
  11. §2.3 Results / p16 (0012.jp2)
  12. §2.4 Discussions / p24 (0016.jp2)
  13. References / p27 (0017.jp2)
  14. Chapter3:DNA Minor Groove Binding Studied by Fluorometric Titration under Pressure:Example of Hoechst 33258 / p29 (0018.jp2)
  15. §3.1 Introduction / p29 (0018.jp2)
  16. §3.2 Materials and Methods / p30 (0019.jp2)
  17. §3.3 Results / p32 (0020.jp2)
  18. §3.4 Discussions / p39 (0023.jp2)
  19. References / p44 (0026.jp2)
  20. Chapter4:Environment-Induced Fluorescence Spectral Shifts of Hoechst 33258 Bound to DNA: Implications for DNA Conformational Changes / p46 (0027.jp2)
  21. §4.1 Introduction / p46 (0027.jp2)
  22. §4.2 Materials and Methods / p47 (0027.jp2)
  23. §4.3 Results / p48 (0028.jp2)
  24. §4.4 Discussions / p59 (0033.jp2)
  25. References / p64 (0036.jp2)
  26. Chapter5:Characterization of in vitro Pressure Effects on Winding of the DNA Helix / p66 (0037.jp2)
  27. §5.1 Introduction / p66 (0037.jp2)
  28. §5.2 Materials and Methods / p67 (0037.jp2)
  29. §5.3 Results and Discussions / p71 (0039.jp2)
  30. References / p85 (0046.jp2)
  31. Chapter6:Summary / p87 (0047.jp2)
  32. Abbreviation / p91 (0049.jp2)
  33. List of Publications / p92 (0050.jp2)
  34. Acknowledgement / p93 (0050.jp2)
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各種コード

  • NII論文ID(NAID)
    500000189183
  • NII著者ID(NRID)
    • 8000000189466
  • DOI(NDL)
  • NDL書誌ID
    • 000000353497
  • データ提供元
    • NDL ONLINE
    • NDLデジタルコレクション
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