The rewarding mechanisms of ethanol under stress
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著者
書誌事項
- タイトル
-
The rewarding mechanisms of ethanol under stress
- 著者名
-
松澤, 茂樹
- 著者別名
-
マツザワ, シゲキ
- 学位授与大学
-
星薬科大学
- 取得学位
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博士 (薬学)
- 学位授与番号
-
乙第100号
- 学位授与年月日
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1999-03-15
注記・抄録
博士論文
目次
- Table of Contents / (0003.jp2)
- General Introduction / p1 (0006.jp2)
- Aim and Scope / p9 (0010.jp2)
- Chapter 1: / p11 (0011.jp2)
- Establishment of Animal Model for Assessing the Rewarding Effect of Ethanol under Physical and Psychological Stresses:Possible Implication of Locomotor-stimulating Effect / p11 (0011.jp2)
- Introduction / p12 (0012.jp2)
- Experiment 1-1.Influence of foot shock stress on motivational effect of ethanol / p15 (0013.jp2)
- Experiment 1-2.Influence of conditioned fear stress on motivational effect of ethanol / p21 (0016.jp2)
- Experiment 1-3.Motivational effects of ethanol,buspirone and diazepam under conditioned fear stress / p27 (0019.jp2)
- Experiment 1-4.Motivational effects of ethanol,buspirone and diazepam under pentylenetetrazole-induced anxiety / p33 (0022.jp2)
- Experiment 1-5.Effects of ethanol,buspirone and diazepam on locomotor activity under conditioned fear stress / p38 (0025.jp2)
- Discussion / p43 (0027.jp2)
- Chapter 2: / p51 (0031.jp2)
- Important Role of the Endogenous Opioid System in the Rewarding Effect of Ethanol under Two Different Stresses:Physical and Psychological Stresses / p51 (0031.jp2)
- Introduction / p52 (0032.jp2)
- Part 1:Foot shock stress / p55 (0033.jp2)
- Experiment 2-1.Effect of non-selective opioid receptor antagonist on ethanol-induced place preference / p55 (0033.jp2)
- Experiment 2-2.Effects of μ-,δ- and k-opioid receptor antagonists and agonists on ethanol-induced place preference / p60 (0036.jp2)
- Part 2:Conditioned fear stress / p67 (0039.jp2)
- Experiment 2-3.Effect of non-selective opioid receptor antagonist on ethanol-induced place preference / p67 (0039.jp2)
- Experiment 2-4.Effects of μ-,δ- and k-opioid receptor antagonists and agonists on ethanol-induced place preference / p72 (0042.jp2)
- Experiment 2-5.Motivational effect of k-opioid receptor agonist / p81 (0046.jp2)
- Discussion / p86 (0049.jp2)
- Chapter 3: / p91 (0051.jp2)
- Involvement of Dopamine D1 and D2 Receptors in the Rewarding Effect of Ethanol under Psychological Stress / p91 (0051.jp2)
- Introduction / p92 (0052.jp2)
- Experiment 3-1.Effects of D1 and D2 receptor antagonists on ethanol-induced place preference under conditioned fear stress / p96 (0054.jp2)
- Experiment 3-2.Effects of D1 and D2 receptor antagonists on enhancement of ethanol-induced place preference produced by μ-opioid receptor agonist under conditioned fear stress / p102 (0057.jp2)
- Experiment 3-3.Effects of D1 and D2 receptor antagonists on enhancement of ethanol-induced place preference produced by δ-opioid receptor agonist under conditioned fear stress / p106 (0059.jp2)
- Discussion / p110 (0061.jp2)
- Chapter 4: / p115 (0063.jp2)
- Involvement of 5-HT3 Receptor in the Rewarding Effect of Ethanol under Psychological Stress / p115 (0063.jp2)
- Introduction / p116 (0064.jp2)
- Experiment 4-1.Effect of 5-HT3 receptor antagonist on ethanol-induced place preference under conditioned fear stress / p118 (0065.jp2)
- Experiment 4-2.Effect of 5-HT3 receptor antagonist on enhancement of ethanol-induced place preference produced by μ-opioid receptor agonist under conditioned fear stress / p123 (0067.jp2)
- Experiment 4-3.Effect of 5-HT3 receptor antagonist on enhancement of ethanol-induced place preference produced by δ-opioid receptor agonist under conditioned fear stress / p127 (0069.jp2)
- Discussion / p131 (0071.jp2)
- Conclusion / p134 (0073.jp2)
- List of Papers / p137 (0074.jp2)
- Acknowledgement / p138 (0075.jp2)
- References / p139 (0075.jp2)