Synthesis, designed assembly, and biological activity of heparin fragments responsible for binding to platelets 血小板結合に関与するヘパリン部分構造の合成と集合化ならびに生物活性に関する研究

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著者

    • 越田, 周平 コシダ, シュウヘイ

書誌事項

タイトル

Synthesis, designed assembly, and biological activity of heparin fragments responsible for binding to platelets

タイトル別名

血小板結合に関与するヘパリン部分構造の合成と集合化ならびに生物活性に関する研究

著者名

越田, 周平

著者別名

コシダ, シュウヘイ

学位授与大学

大阪大学

取得学位

博士 (理学)

学位授与番号

甲第7114号

学位授与年月日

1999-12-14

注記・抄録

博士論文

14401甲第07114号

博士(理学)

大阪大学

1999-12-14

15016

目次

  1. Contents / (0003.jp2)
  2. Symbols and Abbreviations / p1 (0004.jp2)
  3. Chapter I Introduction / p3 (0005.jp2)
  4. Chapter II Synthesis of Oligomer-Model Compounds Containing Two or Three Units of the Key Disaccharide GlcNS6S-IdoA2S / p12 (0010.jp2)
  5. II-1 Introduction and outline of the synthesis / p12 (0010.jp2)
  6. II-2 Synthesis of tail-to-tail type assemblies of the key disaccharides / p16 (0012.jp2)
  7. II-3 Synthesis of a head-to-tail type dimeric assembly of the key disaccharides / p23 (0015.jp2)
  8. II-4 Synthesis of a monomeric key disaccharide by an improved procedure / p27 (0017.jp2)
  9. Chapter III A New Direct Method for Assembly of Sulfated Saccharides by Reductive Amination / p30 (0019.jp2)
  10. III-1 Introduction / p30 (0019.jp2)
  11. III-2 Synthesis of a trisaccharide containing the key disaccharide GlcNS6S-IdoA2S and an additional glucose unit / p31 (0019.jp2)
  12. III-3 Optimization of the reaction conditions for reductive amination / p36 (0022.jp2)
  13. III-4 Synthesis of oligomeric assemblies containing the key disaccharide GlcNS6S-IdoA2S using reductive amination / p42 (0025.jp2)
  14. Chapter IV Platelet-Binding Activities of the Synthetic Oligomers of the Key Disaccharide GlcNS6S-IdoA2S / p46 (0027.jp2)
  15. IV-1 Platelet-binding assay / p46 (0027.jp2)
  16. IV-2 Platelet-binding activities of the synthetic tail-to-tail and the head-to-tail type oligomers / p47 (0027.jp2)
  17. IV-3 Platelet-binding activities of the oligomeric assemblies prepared by reductive amination / p49 (0028.jp2)
  18. Chapter V Synthesis of Partial Oligosaccharides of the AT III-Binding Pentasaccharide Sequence to Identify a Novel Platelet-Binding Site / p52 (0030.jp2)
  19. V-1 Introduction and outline of the synthesis / p52 (0030.jp2)
  20. V-2 Synthesis of a partial trisaccharide of the AT III-binding pentasaccharide and its analogues / p55 (0031.jp2)
  21. V-3 Synthesis of two partial disaccharides of the AT III-binding pentasaccharide / p60 (0034.jp2)
  22. Chapter VI Platelet-Binding Activities of the Partial Oligosaccharides of the AT III-Binding Pentasaccharide / p63 (0035.jp2)
  23. Chapter VII Summary and Conclusion / p66 (0037.jp2)
  24. Chapter VIII Experimental / p70 (0039.jp2)
  25. List of Publications / p149 (0078.jp2)
  26. Acknowledgement / p151 (0079.jp2)
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各種コード

  • NII論文ID(NAID)
    500000189921
  • NII著者ID(NRID)
    • 8000000190204
  • DOI(NDL)
  • NDL書誌ID
    • 000000354235
  • データ提供元
    • 機関リポジトリ
    • NDL ONLINE
    • NDLデジタルコレクション
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