Relationship between Sedentary Behavior and All-cause Mortality in Japanese Chronic Hemodialysis Patients : A Prospective Cohort Study
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著者
書誌事項
- タイトル
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Relationship between Sedentary Behavior and All-cause Mortality in Japanese Chronic Hemodialysis Patients : A Prospective Cohort Study
- 著者名
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菱井, 修平
- 学位授与大学
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香川大学
- 取得学位
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博士(医学)
- 学位授与番号
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甲第737号
- 学位授与年月日
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2020-03-24
注記・抄録
We investigated the relationship between sedentary behavior and all-cause mortality in patients undergoing hemodialysis. A total of 71 patients (39 men, 32 women, aged 72.1±11.7 years) were enrolled in this longitudinal study. Their sedentary behavior was measured using a tri-accelerometer that provides relative values per daily wearing time. We classified the sedentary behavior time into 2 groups (under the median: short-sedentary behavior (SB) group; over the median: long-SB group) and compared the groups’ clinical parameters. We compared the groups’ survival rates by using Kaplan-Meier curves and the log-rank test, and we performed multivariate analyses by a Cox-proportional hazard model to evaluate the relationship between the sedentary behavior and the survival rate. Twenty patients (28.2%) died during the observation period. The survival rate of the short-SB group was significantly higher than that of the long-SB group. Sedentary behavior was thus an important factor for all-cause mortality even after adjusting for confounding factors by a Cox-proportional hazard model. Sedentary behavior is closely linked to all-cause mortality, especially total days and non-hemodialysis days, and reducing sedentary behavior may be beneficial to reduce the all-cause mortality of patients on chronic hemodialysis.
科研費 基盤研究(C) 17K01851
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17K01851/