初流血除去回路つき採血バッグによる皮膚常在菌及び皮膚片の混入の防止

DOI 被引用文献2件 参考文献9件

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  • REDUCTION OF BACTERIAL CONTAMINATION USING A BLOOD COLLECTION SYSTEM WITH INTEGRATED PRE-DONATION DIVERSION POUCH

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In order to decrease the contamination of blood components by bacteria, a diversion pouchintegrated blood collection system is being introduced to blood donation programs in some countries in Europe. The system is designed to collect the first 20-30mL of blood into a diversion pouch before blood collection, thereby eliminating the blood that may be contaminated by the highest number of bacteria residing on the skin. To verify the efficacy of this system on bacterial removal, blood aliquots drawn from the bacteria-coated juglar vein of dogs were serially cultured. It was observed that the number of cfu of bacteria decreased as the pre-donation sampling volume increased and no bacterial colony was detected in tubes after diversion of the first 27.0mL of blood. A blood collection kit for platelet apheresis was integrated with this satellite bag circuit and was tried on a volunteer for platelet collection. No serious problems were encountered except for the unusable volume of 20mL of blood collected in the pouch. The strategy of discarding the first 20-30mL of blood before collection may decrease the rate of bacterial contamination of blood components, especially of apheresis-derived platelet concentrates.

収録刊行物

  • 日本輸血学会雑誌

    日本輸血学会雑誌 49 (6), 761-766, 2003

    一般社団法人 日本輸血・細胞治療学会

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