Lung Cancer with Focal Lymphocytic Interstitial Pneumonia.

• BANDOH Shuji

  The First Department of Internal Medicine, Kagawa Medical University

• FUJITA Jiro

  The First Department of Internal Medicine, Kagawa Medical University

• HABA Reiji

  The Department of Diagnostic Pathology, Kagawa Medical University

• TOJO Yasunori

  The First Department of Internal Medicine, Kagawa Medical University

• HORIIKE Atsushi

  The First Department of Internal Medicine, Kagawa Medical University

• OKAMOTO Taku

  The Second Department of Surgery, Kagawa Medical University

• YOKOMISE Hiroyasu

  The Second Department of Surgery, Kagawa Medical University

• SATOH Katashi

  The Department of Radiology, Kagawa Medical University

• KOBAYASHI Shoji

  The Department of Diagnostic Pathology, Kagawa Medical University

• ISHIDA Toshihiko

  The First Department of Internal Medicine, Kagawa Medical University

抄録

A 65-year-old man was found to have a mass lesion surrounded by ground-glass attenuation in the left upper lobe on chest radiography. He was diagnosed with stage IA adenocarcinoma of the lung. The resected lung specimen revealed papillary adenocarcinoma associated with infiltration of numerous lymphocytes in the alveolar septa, which was consistent with focal lymphocytic interstitial pneumonia (LIP). However, it was not associated with Sjögren's syndrome or any other immunologic abnormalities. Iminunohistochemical study disclosed that CDS positive T-cells constituted the major element of the infiltrated lymphocytes in the tumor, and were also found in the enlarged alveolar septa, suggesting an association between lung cancer and LIP. To our knowledge, this is the first description of an association between LIP and lung cancer. In addition, the focal LIP in this case probably reflected local immune response to an antigenic stimulus caused by lung cancer.<br>(Internal Medicine 41: 997-1001, 2002)

収録刊行物

• Internal Medicine

  Internal Medicine 41 (11), 997-1001, 2002

  一般社団法人 日本内科学会

キーワード

• anti-tumor immunity
• T-cell
• CD8

詳細情報

• CRID: 1390001204867866112
• NII論文ID: 130000767543
• NII論文ID: 50000707088
• NII書誌ID: AA10827774
• DOI: 10.2169/internalmedicine.41.997
• COI: 1:STN:280:DC%2BD38jisVGitA%3D%3D
• ISSN: 13497235
• ISSN: 09182918
• ISSN: http://id.crossref.org/issn/09182918
• NDL書誌ID: 6367045
• PubMed: 12487177
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I6367045
• Web Site: http://www.jstage.jst.go.jp/article/internalmedicine1992/41/11/41_11_997/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2003128162
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可