Usefulness of Brachial-Ankle Pulse Wave Velocity Measurement: Correlation with Abdominal Aortic Calcification.
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- NAKAMURA Udai
- Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
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- IWASE Masanori
- Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
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- NOHARA Sakae
- Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
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- KANAI Hidetoshi
- Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
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- ICHIKAWA Kojiro
- Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
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- IIDA Mitsuo
- Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
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抄録
At present, brachial-ankle pulse wave velocity (baPWV) can be measured easily and noninvasively. We studied the correlation between aortic damage estimated by baPWV and that determined by measuring the length of abdominal aortic calcification (AAC) on X-ray films, which parameter has been significantly associated with cardiovascular morbidity and mortality. baPWV was measured using the form PWV/ankle brachial index (ABI) device in 97 patients free of end-stage renal failure or peripheral arterial disease. baPWV correlated significantly with age (r2 =0.625, p <0.0001), was significantly higher in hypertensives than in normotensives (2, 109±67 vs. 1, 623±93 cm/s, p <0.0001), and correlated significantly with systolic blood pressure (r2 =0.64, p <0.0001) and diastolic blood pressure (r2 =0.397, p <0.0001). baPWV was significantly higher in diabetic patients than in nondiabetics (2, 068±73 vs. 1, 813±97 cm/s, p <0.05), but was similar in normolipidemic and hyperlipidemic patients. baPWV did not correlate with body mass index, fasting plasma glucose, total cholesterol, high density lipoprotein (HDL)-cholesterol, low density lipoprotein (LDL)-cholesterol or triglyceride levels, but correlated significantly with AAC length (r2 =0.599, p <0.0001). Multiple regression analysis indicated that age, systolic blood pressure and AAC length were independent determinants of baPWV. Our results indicate that baPWV is useful for estimating aortic damage and could be a potentially useful predictor of vascular morbidity and mortality. (Hypertens Res 2003; 26: 163-167)
収録刊行物
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- Hypertension Research
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Hypertension Research 26 (2), 163-167, 2003
日本高血圧学会
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詳細情報
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- CRID
- 1390282679695468160
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- NII論文ID
- 130004437034
- 50000753373
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- NII書誌ID
- AA10847079
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- COI
- 1:STN:280:DC%2BD3s7hsVygtA%3D%3D
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- ISSN
- 13484214
- 09169636
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- PubMed
- 12627877
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可