Unusual Fatty Infiltration of the Soleus Muscle in a Patient with Congenital Nemaline Myopathy: Fat-suppression Muscle MRI.

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  • IKEDA Ken
    The Department of Neurology, PL Tokyo Health Care Center The Fourth Department of Internal Medicine, Toho University Ohashi Hospital
  • KINOSHITA Masao
    The Fourth Department of Internal Medicine, Toho University Ohashi Hospital
  • IWASAKI Yasuo
    The Fourth Department of Internal Medicine, Toho University Ohashi Hospital
  • ICHIKAWA Yasumitsu
    The Fourth Department of Internal Medicine, Toho University Ohashi Hospital
  • YABUKI Daisuke
    The Fourth Department of Internal Medicine, Toho University Ohashi Hospital
  • WAKATA Nobuo
    The Fourth Department of Internal Medicine, Toho University Ohashi Hospital
  • NONAKA Ikuya
    Division of Ultrastructural Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry

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A 27-year-old man developed gait disturbance over a three-year period. Histochemical analysis suggested nemaline bodies, type I fiber atrophy and type II fiber hypertrophy. Conventional magnetic resonance imaging (MRI) showed a severe degree of homogenous hyperintensity in the soleus muscle. Fat-suppression MRI exhibited marked diffuse hypointensity in the soleus muscle. MRIs demonstrated unusual fatty proliferation of the soleus muscle. Fat-suppression MRI of skeletal muscles is beneficial in evaluating the accurate topography and degree of fatty infiltration. Radiological patterns of muscle damage are variable in patients with congenital nemaline myopathy, similar to the heterogeneous clinical aspects.<br>(Internal Medicine 41: 237-240, 2002)

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  • Internal Medicine

    Internal Medicine 41 (3), 237-240, 2002

    一般社団法人 日本内科学会

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