書誌事項
- タイトル別名
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- OK432 chemical pleurodesis as a standard therapy of spontaneous pneumothrax.
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To establish a standard therapy for spontaneous pneumothorax, we evaluated 155 cases with spontaneous pneumothorax between 1980 and 1986, especially in terms of the outcome, side effects and loss of pulmonary function in 92 cases treated with OK432 chemical pleurodesis.<br>Fever, chest pain, pleural effusion and thickening were recognized in almost all cases after intrapleural administration of OK432, however fever and chest pain subsided within a week, and pleural effusion and thickening disappeared within 2 months without any further treatment.<br>The recurrence rate after treatment was 21.4% in cases treated by rest and/or aspiration, 30% in cases treated by drainage and 12.4% in cases treated by OK432 chemical pleurodesis respectively. A pulmonary function study 2-6 months after OK432 chemical pleurodesis showed no significant loss in %VC (90.3±20.2), FEV (84.4±8.6) or other parameters. But this method should be avoided in patients with poor pulmonary function because of the possibility of worsening the condition.<br>We conclude that OK432 chemical pleurodesis is adequate as a standard therapy for spontaneous pneumothorax, because of its low recurrence rate, tolerable side effects and negligible loss of pulmonary function.
収録刊行物
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- 日本胸部疾患学会雑誌
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日本胸部疾患学会雑誌 26 (1), 10-15, 1988
社団法人 日本呼吸器学会