閉経婦人の高脂血症に対するエストロゲン剤とシンバスタチンの治療成績

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  • Estrogen/Simvastatin Combination Therapy in Hypercholesterolemic Postmenopausal Women.

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A study was performed to evaluate the combined effect of hormone replacement therapy (HRT) and an HMG-CoA reductase inhibitor simvastatin on lipid profile in postmenopausal women with hypercholesterolemia. 13 (46.4%) of 28 surgical menopausal women (A) and 48 (46.2%) of 104 natural menopausal women (B) had hypercholesterolemia (cholesterol>220 mg/dl).<br>After our protocol with three months of HRT, the number of women with hypercholesterolemia decreasd to 9 (32.1%) of 28 in group A and 35 (33.7%) of 104 in group B. After 3 months of combination treatment with HRT and Simvastatin, the number of women with hypercholesterolemia decreased to 4 (14.3%) of 28 in group A and 18 (17.3%) of 104 in group B.<br>It is concluded that we can expect to improve the quality of life of postmenopausal women by doing the active examination of lipid, education of life style and treatment.

収録刊行物

  • 医療

    医療 50 (12), 811-815, 1996

    一般社団法人 国立医療学会

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