抄録
<jats:p>According to the signal hypothesis, a signal sequence, once having initiated export of a growing protein chain across the rough endoplasmic reticulum, is cleaved from the mature protein at a specific site. It has long been known that some part of the cleavage specificity resides in the last residue of the signal sequence, which invariably is one with a small, uncharged side‐chain, but no further specific patterns of amino acids near the point of cleavage have been discovered so far. In this paper, some such patterns, based on a sample of 78 eukaryotic signal sequences, are presented and discussed, and a first attempt at formulating rules for the prediction of cleavage sites is made.</jats:p>
収録刊行物
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- European Journal of Biochemistry
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European Journal of Biochemistry 133 (1), 17-21, 1983-06
Wiley
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キーワード
詳細情報 詳細情報について
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- CRID
- 1361137044291722496
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- NII論文ID
- 80001717006
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- ISSN
- 14321033
- 00142956
- http://id.crossref.org/issn/00142956
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- データソース種別
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- Crossref
- CiNii Articles