Olfactory Recognition: A Simple Memory System

  • Peter Brennan
    Sub-Department of Animal Behaviour, University of Cambridge,Madingley, Cambridge, United Kingdom CB3 8AA.
  • Hideto Kaba
    Department of Anatomy, University of Cambridge, Cambridge, United Kingdom CB3 8AA.
  • Eric B. Keverne
    Sub-Department of Animal Behaviour, University of Cambridge,Madingley, Cambridge, United Kingdom CB3 8AA.

抄録

<jats:p>Mice have an olfactory (pheromone) recognition memory located at the first relay in the sensory system. It is acquired with one-trial learning, contingent upon norepinephrine activation at mating, and lasts for several weeks. The mechanism involves Hebbian (association-dependent) changes in synaptic efficacy at dendrodendritic synapses in the accessory olfactory bulb. As a result of this memory, males made familiar by mating are recognized by the females, thereby mitigating pregnancy block. Such a memory function is biologically important to the female, as it is required to sustain pregnancy in the presence of her stud male's odors.</jats:p>

収録刊行物

  • Science

    Science 250 (4985), 1223-1226, 1990-11-30

    American Association for the Advancement of Science (AAAS)

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