薬物の組織分布に関する機構論的解析

書誌事項

タイトル別名
  • Analysis of Drug Distribution Mechanism in Tissues.

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抄録

To develop novel strategies for tissue selective drug delivery, studies on drug distribution mechanism in tissues have become more important. The present review focus on some of the important factors that should be considered in regulating the drug distribution in tissues, i.e., tissue binding, plasma binding and membrane permeability. Especially, a role of specific transport system has been discussed to utilize for the drug permeation pathway at the tissue plasma membrane.

収録刊行物

  • 薬物動態

    薬物動態 7 (5), 643-652, 1992

    日本薬物動態学会

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