血小板保存液“セト液”の臨床使用

DOI 被引用文献12件

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タイトル別名
  • Clinical application of platelet storage "Seto solution".

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In order to prevent adverse effects associated with the transfusion of platelet concentrates, the plasma in platelet concentrates was removed into another bag connected with a sterile connecting device and platelets were resuspended in the Seto solution. Average percentages of the plasma removal and the recovery of platelet were 94.4% and 93.8%, respectively. Platelets suspended in Seto solution were transfused 131 times into 22 patients who had showed adverse effects such as fever and urticarial rash and might exhibit hemolysis due to ABO-incompatible platelet transfusion. The average recovery of transfused platelets in vivo was 53% one day after platelet transfusion. This value was similar to that of the transfusion of platelet concentrates (55%). The adverse effects associated with platelet transfusions were remarkably decreased using Seto solution but developed in 2 cases. These results indicate that Seto solution is very useful to prevent the adverse effects due to plasma components.

収録刊行物

  • 日本輸血学会雑誌

    日本輸血学会雑誌 40 (4), 589-592, 1994

    一般社団法人 日本輸血・細胞治療学会

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