Changes in Auxin Response from Mutations in an <i>AUX/IAA</i> Gene

  • Dean Rouse
    D. Rouse, P. Mackay, P. Stirnberg, O. Leyser, Department of Biology, University of York, York YO1 5YW, UK.
  • Pamela Mackay
    D. Rouse, P. Mackay, P. Stirnberg, O. Leyser, Department of Biology, University of York, York YO1 5YW, UK.
  • Petra Stirnberg
    D. Rouse, P. Mackay, P. Stirnberg, O. Leyser, Department of Biology, University of York, York YO1 5YW, UK.
  • Mark Estelle
    D. Rouse, P. Mackay, P. Stirnberg, O. Leyser, Department of Biology, University of York, York YO1 5YW, UK.
  • Ottoline Leyser
    D. Rouse, P. Mackay, P. Stirnberg, O. Leyser, Department of Biology, University of York, York YO1 5YW, UK.

抄録

<jats:p> Transcription of the <jats:italic>AUX/IAA</jats:italic> family of genes is rapidly induced by the plant hormone auxin, but evidence that <jats:italic>AUX/IAA</jats:italic> genes mediate further responses to auxin has been elusive. Changes in diverse auxin responses result from mutations in the <jats:italic>Arabidopsis AXR3</jats:italic> gene. <jats:italic>AXR3</jats:italic> was shown to be a member of the <jats:italic>AUX/IAA</jats:italic> family, providing direct evidence that <jats:italic>AUX/IAA</jats:italic> genes are central in auxin signaling. Molecular characterization of <jats:italic>axr3</jats:italic> gain-of-function and loss-of-function mutations established the functional importance of domains conserved among AUX/IAA proteins. </jats:p>

収録刊行物

  • Science

    Science 279 (5355), 1371-1373, 1998-02-27

    American Association for the Advancement of Science (AAAS)

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