Daidzein and genistein but not their glucosides are absorbed from the rat stomach

DOI Web Site Web Site Web Site 被引用文献21件

抄録

<jats:p>Absorption of isoflavone aglycones and glucosides was compared in rats. Daidzein, genistein, daidzin and genistin were orally administered at a dose of 7.9 μmol/kg in 25 mM Na<jats:sub>2</jats:sub>CO<jats:sub>3</jats:sub> and next their metabolite concentration in blood plasma was monitored for 30 min. After isoflavone glucosides administration, their metabolites appeared in plasma with a few minutes delay as compared to aglycones, which suggested that aglycones, but not glucosides, were absorbed already in the rat stomach. This observation was confirmed when absorption site was restricted solely to the stomach and absorption was shown to be independent of the vehicle pH used for administration.</jats:p>

収録刊行物

  • FEBS Letters

    FEBS Letters 447 (2-3), 287-291, 1999-03-26

    Wiley

被引用文献 (21)*注記

もっと見る

キーワード

問題の指摘

ページトップへ