Genome Sequence of the Radioresistant Bacterium <i>Deinococcus radiodurans</i> R1

DOI Web Site 被引用文献28件
  • Owen White
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • Jonathan A. Eisen
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • John F. Heidelberg
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • Erin K. Hickey
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • Jeremy D. Peterson
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • Robert J. Dodson
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • Daniel H. Haft
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • Michelle L. Gwinn
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • William C. Nelson
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • Delwood L. Richardson
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • Kelly S. Moffat
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • Haiying Qin
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • Lingxia Jiang
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • Wanda Pamphile
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • Marie Crosby
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • Mian Shen
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • Jessica J. Vamathevan
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • Peter Lam
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • Lisa McDonald
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • Terry Utterback
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • Celeste Zalewski
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • Kira S. Makarova
    National Center for Biotechnology Information, National Library of Medicine, Bethesda, MD 20894, USA.
  • L. Aravind
    National Center for Biotechnology Information, National Library of Medicine, Bethesda, MD 20894, USA.
  • Michael J. Daly
    Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
  • Kenneth W. Minton
    Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
  • Robert D. Fleischmann
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • Karen A. Ketchum
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • Karen E. Nelson
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • Steven Salzberg
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • Hamilton O. Smith
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • J. Craig
  • Venter
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
  • Claire M. Fraser
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.

抄録

<jats:p> The complete genome sequence of the radiation-resistant bacterium <jats:italic>Deinococcus radiodurans</jats:italic> R1 is composed of two chromosomes (2,648,638 and 412,348 base pairs), a megaplasmid (177,466 base pairs), and a small plasmid (45,704 base pairs), yielding a total genome of 3,284,156 base pairs. Multiple components distributed on the chromosomes and megaplasmid that contribute to the ability of <jats:italic>D. radiodurans</jats:italic> to survive under conditions of starvation, oxidative stress, and high amounts of DNA damage were identified. <jats:italic>Deinococcus radiodurans</jats:italic> represents an organism in which all systems for DNA repair, DNA damage export, desiccation and starvation recovery, and genetic redundancy are present in one cell. </jats:p>

収録刊行物

  • Science

    Science 286 (5444), 1571-1577, 1999-11-19

    American Association for the Advancement of Science (AAAS)

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