性器クラミジア感染症の臨床病態と病理組織細胞学的検討

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  • The study of the clinical symptom and histocytological pathology of Chlamydia trachomatis infection disease in the genital organs
  • セイキ クラミジア カンセンショウ ノ リンショウ ビョウタイ ト ビョウリ ソシキ サイボウガクテキ ケントウ

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Chlamydia trachomatis infection is now well recognized as one of sexually transmitted diseases (STD) . The study was performed to analyze an accuracy of diagnostic procedures and their relation to clinical stages. We analyzed the disease serologically detected method using antibody againist Chlamydia trachomatis and microscopic observation on smears staind with Papanicolaou and immunohistochemical staining using anti-Chlamydia trachomatis antibody. Serum antibody titer levels of IgA and IgG were high to be closely related to clinical stages of the disease. For instance, 5 out of 6 cases with Fitz-Hugh-Curtis syndrome showed very high level of serum antibody titer. Cytologically, intracytoplasmic inclusion bodies were observed in metaplastic epithelial cells of vaginal smears with Papanicolaou staining. These inclusion bodies were also positive for smears with immunohistochemical staining using anti-Chlamydia trachomatis antibody. In addition, cytological results also showed a close correlation to serum antibody titer and to clinical stages of the diease. It was, therefore, revealed that above methods are quite useful to make a diagnosis of Chlamydia trachomatis infection.

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