Effect of Flow Baffles on the Dialysate Flow Distribution of Hollow-Fiber Hemodialyzers: A Nonintrusive Experimental Study Using MRI

DOI PDF 被引用文献6件
  • Churn K. Poh
    Department of Mechanical Engineering, University of Kentucky, Lexington, KY
  • Peter A. Hardy
    Center for Biomedical Engineering, University of Kentucky, Lexington, KY
  • Zhijie Liao
    Department of Mechanical Engineering, University of Kentucky, Lexington, KY
  • Zhongping Huang
    Department of Mechanical Engineering, University of Kentucky, Lexington, KY
  • William R. Clark
    Rental Division, Baxter Healthcare Corporation, McGaw Park, IL
  • Dayong Gao
    Department of Mechanical Engineering, University of Kentucky, Lexington, KY

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<jats:p>We used an innovative, nonintrusive MRI technique called the two-dimensional (2D) Phase-Contrast (2DPC) velocity-imaging technique to investigate the effect of flow baffles on the dialysate-side flow distribution in two different hollow-fiber hemodialyzers (A and B); each with flow rates between 200 and 1000 mL/min (3.33×10−6 and 1.67×10−5 m3/s). Our experimental results show that (1) the dialysate-side flow distribution was nonuniform with channeling flow occurred at the peripheral cross section of these hollow-fiber hemodialyzers, and (2) the existing designs of flow baffles failed to promote uniform dialysate-side flow distribution for all flow rates studies.</jats:p>

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