Biocatalysts in organic syntheses : proceedings of an international symposium organized under auspices of the Working Party on Immobilized Biocatalysts of the European Federation of Biotechnology, Noordwijkerhout, the Netherlands, 14-17 April, 1985

Bibliographic Information

Biocatalysts in organic syntheses : proceedings of an international symposium organized under auspices of the Working Party on Immobilized Biocatalysts of the European Federation of Biotechnology, Noordwijkerhout, the Netherlands, 14-17 April, 1985

edited by J. Tramper, H.C. van der Plas, and P. Linko

(Studies in organic chemistry, 22)

Elsevier, 1985

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Description and Table of Contents

Description

Many interesting chemical reactions that are difficult or impossible to accomplish by ordinary chemical means are efficiently catalysed by enzymes in microbial, plant and animal cells. The lack of communication between organic chemists and biotechnologists is an important factor limiting the number of synthetic applications of biocatalysts. This book contains most of the presentations of an international symposium which was held to try and bring the groups together. A total of 225 participants attended the symposium, with about one half biotechnologists and one half organic chemists, demonstrating the interest of the former in applying enzymic methods in organic reactions and of the latter in looking for enzymes as tools in organic methodology.

Table of Contents

Session 1. Enzymes as Catalysts: Potential and Limitations. The scope of biocatalysts in organic chemical processing (S.E. Godtfredsen et al.). Microbial enzymes as catalysts for synthesis of biologically useful compounds (H. Yamada, S. Shimizu). II. Central Problems and Trends in Organic Syntheses. Chiral intermediates as building blocks (W. Graf). Advantages and limitations of chemical optical resolution (R.A. Sheldon et al.). III. What can Biotechnology do for the Chemical Industry/Research? Microbiologically catalysed reaction steps in the field of vitamin and carotenoid syntheses (H.G.W. Leuenberger). Enzymatic preparation of optically active alcohols related to synthetic pyrethroids insecticides (H. Hirohara et al.). Use of biocatalysts in the industrial production of speciality chemicals (E.M. Meijer et al.). IV. Broadening the Scope of Applications of Biocatalysts. Immobilized biocatalysts in organic synthesis and chemical production (Y.-Y. Linko, P. Linko). Biocatalytic reactions involving water-insoluble organic compounds (M.D. Lilly, J.M. Woodley). V. Specific/Future Applications. Interesterification of fats and oils (A.R. Macrae). Polymerizations that use biocatalysts (E.S. Lipinsky). Syntheses by plant cells (A.W. Alfermann). Future applications including protein engineering (B. Witholt et al.). Author Index.

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