The Importance of laboratory animal genetics, health, and the environment in biomedical research

著者

• Charles River International Symposium on Laboratory Animals
• Melby, Edward C.
• Balk, Melvin W.

書誌事項

The Importance of laboratory animal genetics, health, and the environment in biomedical research

edited by Edward C. Melby, Jr., Melvin W. Balk

Academic Press, 1983

注記

"Proceedings of the Fifth Charles River International Symposium on Laboratory Animals, "Biomedical Research: The Importance of Laboratory Animal Genetics, Health, and the Environment," held in Heidelberg, Federal Republic of Germany, March 14-16, 1983." -- facing t.p.

Includes bibliographies and index

内容説明・目次

内容説明

The Importance of Laboratory Animal Genetics, Health, and the Environment in Biomedical Research documents the proceedings of the Fifth Charles River International Symposium on Laboratory Animals, in Heidelberg, Federal Republic of Germany, March 14-16, 1983. These papers examine how the health and genetic monitoring of laboratory animals, coupled with environmental influences, affect the investigations of oncologists, toxicologists, or pharmacologists. The book is organized into four parts. Part I focuses on the health monitoring of laboratory animals for biomedical research. It includes studies on the effects of health and health monitoring in toxicology studies, oncology studies, and pharmacologic studies. Part II deals with the genetic monitoring of laboratory animals. It examines the causes of genetic alternation in laboratory animals and ways to prevent them. Part III considers the environmental monitoring that is necessary for research on laboratory animals. Part IV on new research frontiers includes studies on the production of monoclonal antibodies for the experimental and therapeutic modulation of laboratory animals, and the quality control aspects of animal experimentation.

目次

Contributors Participants Preface Introductory Remarks Part I Health Monitoring: Interpretation and Importance to Biomedical Research Overview of the State of the Art in Health Monitoring The Effects of Health and Health Monitoring on Toxicology Studies The Effects of Health and Health Monitoring on Oncology Studies The Effects of Health and Health Monitoring on Pharmacologic Studies Part II Genetic Monitoring: Interpretation and Importance to Biomedical Research Overview of the State of the Art in Genetic Monitoring Malformations of Genetic Origin in Teratology Studies: Cases of Cleft Palate in Rabbits The Impact of Genetics and Genetic Monitoring on Oncological Studies-Some Aspects of Leukemogenesis in the AKR Strain Impact of Genetics and Genetic Monitoring on Pharmacology Studies Part III Environmental Monitoring: Interpretation and Importance to Biomedical Research Overview of the State of the Art in Environmental Monitoring The Effects of Environment and Environmental Monitoring on Toxicology Studies The Effects of Environment and Environmental Monitoring on Oncology Studies The Effects of Environment and Environmental Monitoring on Pharmacology Studies Part IV New Research Frontiers: Importance of the Laboratory Animal Monoclonal Antibodies-Importance of the Laboratory Animal The Importance of Laboratory Animal Genetics, Health, and Environment-The Laboratory Animal Specialist's Viewpoint Quality Animals for Biomedical Research: Lessons from the Past, Opportunities for the Future MHC, Mice, Men, and Businessmen Index

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詳細情報

• NII書誌ID(NCID): BA00380062
• ISBN:
  • 0124895204
• LCCN: 83021520
• 出版国コード: us
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: Orlando
• ページ数/冊数: xv, 284 p.
• 大きさ: 24 cm
• 分類:
  • LCC : QL55
  • DC19 : 619
• 件名:
  • LCSH : Laboratory animals -- Congresses