Selective neuronal death
著者
書誌事項
Selective neuronal death
（Ciba Foundation symposium, 126）
Wiley, 1987
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注記
"Symposium on Selective Neuronal Death, held at the Ciba Foundation, London, 15-17 Apr. 1986"--Contents p
Editors: Gregory Bock (organizer) and Maeve O'Connor
"A Wiley-Interscience publication."
Includes bibliographies and indexes
内容説明・目次
内容説明
Parkinson's disease, Alzheimer's disease, and motor neuron disease (amyotrophic lateral sclerosis) share a significant common feature: selective death of neurons in restricted regions of the brain. In this international symposium - the first to bring together neurophysiologists working on neuronal death and neuropathologists dealing with human degenerative brain disease - the participants describe the causes and sequence of events leading to neuronal death and discuss what can be done to prevent it. Among the topics covered in the symposium are recent advances in the understanding of agents that are known to be involved in neuronal death, examples of neuronal death during normal development, and the role played by endocrine mechanisms and neuronal activity. These topics are discussed in relation to possible causes of specific human diseases. Trophic factors controlling the survival of neuronal transplants are considered, as are the therapeutic prospects for tissue transplantation. This interdisciplinary symposium summarizes the most recent information on these degenerative brain diseases and suggests new directions for research.
Neurobiologists, neuropathologists, clinical neurologists, psychiatrists and cell biologists will all find this book stimulating. It should also interest clinicians, particularly those working in geriatric medicine.
目次
Partial table of contents:. Nerve Cell Death in Degenerative Diseases of the Central Nervous System: Clinical Aspects (Y. Agid & J. Blin). Dysfunction and Death of Neurons in Human Degenerative Neurological Diseases and in Animal Models (D. L. Price, et al.). Neuronal Origin of Cerebral Amyloidogenic Proteins: Their Role in Alzheimer's Disease and Unconventional Virus Diseases of the Nervous System (C. L. Masters & K. Beyreuther). Mechanism for Programmed Cell Death in the Nervous System of a Moth (S.E. Fahrbach & J. W. Truman). Neurotrophic Factors and Neuronal Death (H. Thoenen, et al.). Muscle Activity and Motor Neuron Death in the Spinal Cord of the Chick Embryo (R. W. Oppenheim). Remodelling of Early Axonal Projections Through the Selective Elimination of Neurons and Long Axon Collaterals (D. D. M. O'Leary).
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