The genetics of the skeleton : animal models of skeletal development

Bibliographic Information

The genetics of the skeleton : animal models of skeletal development

D.R. Johnson

(Oxford science publications)

Clarendon Press , Oxford University Press, 1986

Available at  / 12 libraries

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Note

Includes bibliographies and index

Description and Table of Contents

Description

Johnson's book describes the effects of genetic mutations on the mammalian skeleton, and their usefulness as a tool to help us understand how the skeleton develops. Using the mouse as a primary source, but with mutations in other laboratory animals discussed where appropriate, the author considers the precartilaginous (mesenchymal), cartilaginous, and bony skeletons, regional anatomy (axial and appendicular skeletons, the skull, face, palate, and teeth), and the interactions between genes and teratogens. Each chapter consists of a summary covering the development of a particular area or topic, followed by a consideration of mutants and how they affect the area. A short synthesis discusses the contributions that mutants make to our understanding of the development of each area considered.

Table of Contents

  • Models of disease processes
  • The membranous skeleton
  • The cartilaginous skeleton
  • The bony skeleton
  • The axial skeleton
  • The skull, face, and palate
  • The teeth
  • The limbs
  • Genes and teratogens
  • Appendices
  • Index.

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