Insect aging : strategies and mechanism

書誌事項

Insect aging : strategies and mechanism

edited by K.-G. Collatz and R.S. Sohal

Springer-Verlag, c1986

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  • : wb

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注記

Bibliography: p. 234-236

Includes index

内容説明・目次

内容説明

"Leben ist die schonste Erfindung der Natur und der Tod ist ihr Kunstgriff, viel Leben zu haben" . J. W. v. Goethe Life is the most beautiful invention of nature, and death is her device to exhibit most life. The eminent British biologist Sir Vincent B. Wigglesworth noted in 1939 that insects are an ideal medium in which to study all problems of physiology. Many fundamental discoveries in biology, particularly genetics and development, have been made on the basis of studies conducted in insects. Because of their ex- treme adaptability and diversity, an appropriate insect model is available for the study of virtually any biological problems. The applicability to other groups, including mammals, of basic studies conducted on insects has helped in the gradual acceptance of the fundamental unity of biochemical principles as a dogma among biologists, as well as among enlightened medical scientists. With the recent upsurge of interest in the study of the aging process, in- sects have been increasingly employed not only for the investigation of basic mechanisms of aging, but also to gain insight into the evolution of aging and senescence. If only one aging mechanism exists, it is foreseeable that some in- sects, especially Drosophila, will help to unravel its molecular basis. Because of their diversity, existing studies in the gerontology of insects are widely scat- tered in various specialized journals. This wealth of existing information has not, as yet, been brought together in a synthesized and comprehensive form.

目次

Towards a Comparative Biology of Aging.- Critical Points in Time and Their Influence on Life Cycle, Life Span and Aging.- The Rate of Living Theory: A Contemporary Interpretation.- Sexual Activity and Life Span.- Aging of Flight Mechanism.- Radiation and Longevity Enhancement in Tribolium.- Brain Aging in Insects.- Programmed Cell Death and Aging.- Structural Correlates of Aging in Drosophila: Relevance to the Cell Differentiation, Rate-of-Living and Free Radical Theories of Aging.- Role of Mitochondria in Drosophila Aging.- Metal Ions, Mitochondrial DNA and Aging.- Age-related Changes in Cell Nuclei.- Role of Glutathione in the Aging and Development of Insects.- Role of Steroids in Aging.- Protein Synthesis in Relation to Insect Aging: An Overview.- Effect of Aging on the Components of the Protein Synthesis System.- Genetics of Aging: Effective Selection for Increased Longevity in Drosophila.

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