Patterson and Pattersons : fifty years of the Patterson function : proceedings of a symposium held at the Institute for Cancer Research, the Fox Chase Cancer Center, Philadelphia, PA, USA, November 13-15, 1984

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Patterson and Pattersons : fifty years of the Patterson function : proceedings of a symposium held at the Institute for Cancer Research, the Fox Chase Cancer Center, Philadelphia, PA, USA, November 13-15, 1984

edited by Jenny P. Glusker, Betty K. Patterson, and Miriam Rossi

（Crystallographic Symposia, v. 1）

Clarendon Press , Oxford University Press, 1987

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

It was a milestone in the development of the young science of crystallography when in 1934 A.L.Patterson's first paper on the |F| 2 series appeared. The "Patterson Function" has opened entirely new avenues to the solution of crystal structures and continues to be a widely used tool. To celebrate the 50th anniversary of Patterson's discovery, a Symposium, "Patterson and Pattersons. Fifty Years of the Patterson Function" was held on 13-15 November, 1984 at the Fox Chase Cancer Center in Philadelphia, Pennsylvania. The title of the symposium and its proceedings portrays the spirit of the meeting. In addition to the lectures and contributions which deal with the theory and the applications of the "Patterson Function", as well as other modern aspects of crystallography, the volume contains many personal reminiscences of Lindo Patterson by his widow and by contemporaries and friends.

目次

  • PART I: INTRODUCTION
  • Patterson functions
  • Harker sections
  • Homometric structures. PART II: PROGRAM OF FOX CHASE SYMPOSIUM: A CELEBRATION OF THE PATTERSON FUNCTION: Introduction
  • The impact of the Patterson function
  • Emerging new methodologies in the imaging of nanostructures
  • Chemical information from crystal structures
  • Protein structure and function
  • Some experiences with the Patterson function in protein crystallography
  • Patterson and Pattersons
  • The nanometer world of hydrogen bonds
  • Electron density maps
  • Rational design of DNA-binding drugs or How to read a helix
  • DNA-protein interactions. PART III: CONTRIBUTED PAPERS: A. METHODS: Patterson's 'symmetry map' interpretation of Patterson's function
  • On the paper entitled 'Detection of inversion centers using the Patterson function'
  • A connection between the Patterson function and direct methods
  • Computer-aided analysis of multi-solution Patterson superpositions
  • Integration of Patterson search and direct methods - a novel strategy for the solution of difficult crystal structures
  • Introduction to rotation and translation functions
  • The relationship between feedback methods and ismorphous difference Pattersons in the solution of biological macromolecules
  • Searching for non-crystallographic rotational symmetry in Patterson space
  • Automation of rotation functions in vector space
  • Equal atom Patterson methods: practical experience with rotation and translation functions for the solution of the phase problem for crystal structures of complex organic molecules
  • Computing in crystallography: the early days
  • The Patterson-Tunell strip method for the summation of Fourier series
  • Early use of the Patterson function at Caltech
  • Patterson methods in the determination of the structure of -ketoglutarate
  • X-ray imaging of quantum electron structure
  • Looking backward: On certain Fourier and Patterson maps
  • Absolute configuration of natural products using anomalous dispersion of light atoms
  • B. THE PATTERSON FUNCTION APPLIED TO ADVANCES IN THE BIOLOGICAL SCIENCES: Model building and structural studies for the DNA-binding protein cII
  • Active site homology in iron and manganese superoxide dismutases
  • On the structure of a biological crystal determined by its Patterson function
  • Localization of the Cu2+ atom in the unit cell of crystals of Ps. denitrificans azurin utilizing synchrotron-induced anomalous dispersion
  • Comparison of X-ray crystallography and solution small-angle scattering: morphological parameters of globular proteins as corroborated by hydrodynamics
  • The Patterson function in fiber diffraction
  • The Patterson function and membrane diffraction
  • C. HOMOMETRICS: Homometrics
  • Homometric structures
  • Some recollections about Patterson and homometric sets. PART IV: PATTERSON - THE MAN AND THE SCIENTIST.

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