Membrane transport of antineoplastic agents

書誌事項

Membrane transport of antineoplastic agents

section editor, I. David Goldman

(International encyclopedia of pharmacology and therapeutics, section 118)

Pergamon Press, 1986

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注記

"Published as a supplement no. 18 (1985) to the review journal Pharmacology and therapeutics"--T.p. verso

Includes bibliographies and index

内容説明・目次

内容説明

This volume comprehensively covers the membrane dynamics of anticancer drug action. Each chapter deals with specific drugs and discusses the pharmacokinetics of the drug at all major sites of activity. By dealing with the dynamics of the drugs at the membrane level the fundamental aspects of drug action are considered in all organs that are important to the clinical oncologist. The accumulation of this knowledge in a single volume will be a great advance in the chemotherapy of cancer, and an excellent manual for students, trainees and researchers who wish to study this phenomenon.

目次

  • Mechanisms of transmembrane transport in isolated cells and their experimental study, J A Schafer & D W Barfu
  • s. Physiological pharmacokinetics: an in vivo approach to membrane transport, R L Lutz et al. Application of network thermodynamics to the computer modelling of the pharmacology of anticancer agents: a network model for methotrexate action as a comprehensive example, J C White & D C Mikul
  • cky. Methods for quantifying the transport of drugs across brain barrier systems, J D Fenstermacher et al. Gastrointestinal absorption of folates and antifolates, J Selhub et al. Liposomes as drug carriers in cancer chemotherapy, J N Weinstein & L D Leser
  • an. Membrane transport of anthrocyclines, T Skovsgaard & N I Nisse
  • . Genetic and biochemical characterization of multidrug resistance, J R Riordan & V Ling.
  • orrelates of folate analog transport, pharmacokinetics and selective antitumor action, F M Sirotnak. The cellular pharmacology of methotrexate, I D Goldman & L H Mathe
  • ly. Transport of nucleoside drugs in animal cells, A R P Paterson & C E Cass.
  • Membrane transport of alkylating agents, G J Goldenberg & A Berglei
  • er. Cellular pharmacokinetics of the phenylalanine mustards, D T Vistica. Index.

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