Cardiovascular disease : molecular and cellular mechanisms, prevention, and treatment
著者
書誌事項
Cardiovascular disease : molecular and cellular mechanisms, prevention, and treatment
（GWUMC Department of Biochemistry annual spring symposia）
Plenum Press, c1987-
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- 2
- タイトル別名
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Cardiovascular disease 2
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注記
Based on papers presented at the Sixth International Spring Symposium on Health Sciences, held in Washington, D.C. in May 1986
2:Proceedings of the fourteenth Washington International Spring Symposium at the George Washington University, held June 6-10, 1994, in Washington, D.C.
Includes bibliographies and index
内容説明・目次
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[1] ISBN 9780306425370
内容説明
The Sixth Annual International Spring Symposium on Health Sciences, held in Washington, D. C., in May 1986, brought together over 650 scientists from 19 countries to review and update research on cardiovascular disease. In this volume, which contains 59 chapters, an internationally recognized group of authors con tribute up-to-date accounts of molecular and cellular processes occurring in the vessel wall in atherogenesis and describe approaches to the prevention and treatment of atherosclerosis. The volume is divided into six major sections. Two sections deal with current aspects of lipoprotein metabolism. In Part I, we are alerted to the impact on li poprotein metabolism of structural heterogeneity within the four broad lipoprotein classes. Attention then turns to the components that orchestrate lipoprotein metab olism. Apolipoprotein identities, processing, and functions are described, as are the roles of lipid transfer proteins in plasma lipoprotein remodeling. Hepatic lipase synthesis and secretion are described. In Part II, Nobel Laureates Michael S. Brown and Joseph L. Goldstein describe mutations in the LDL receptor that reveal the functions of its various domains and point out how understanding the LDL receptor has provided a rational basis for its regulation. A discussion of the role of receptors in regulating cholesterol uptake by tissues follows, with emphasis on receptor-ligand interactions. Additional pathways for cholesterol delivery to cells are explored, as are pathways for cholesterol egress."
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2 ISBN 9780306449925
内容説明
Proceedings of the Fourteenth Washington International Spring Symposium, held in Washington, D.C., June 1994, to review and update research on cardiovascular disease. The volume is divided into eight sections which reflect the focus of the plenary sessions: atherogenesis; atherogenic lipoproteins; a
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