書誌事項

Oncogenes

editors, Takis S. Papas, George F. Vande Woude

(Gene amplification and analysis, v. 4)

Elsevier, c1986

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注記

Includes bibliographies and index

内容説明・目次

内容説明

Oncogenes were first discovered as part of the genome of acute transforming retroviruses. This comprehensive and timely work furthers our understanding of the genetic makeup and mechanism of action of oncogenes. The fourth volume in a series that conveys vital information to scientists working in recombinant genetics and molecular biology, Oncogenes brings together recent findings derived from DNA transfection and transformation assays. International contributors analyze and assess oncogenes from a variety of perspectives to present the latest knowledge. Providing useful information on a topic vital to today's research in molecular oncology, Oncogenes is a valuable update for all those working in the field of genetic engineering.

目次

Preface. Contributors. Chapter 1. Structural and Functional Motifs of the Rous Sarcoma Virus Scr Protein. Chapter 2. Activation of ras Oncogenes by Chemical Carcinogens. Chapter 3. Sequences 3' of the Human c-Ra-ras1 Gene Positively Regulate its Expression and Transformation Potential. Chapter 4. Structure and Function of p21 ras Proteins. Chapter 5. The myb Oncogene. Chapter 6. Structure and Mechanism of Activation of the myb Oncogene. Chapter 7. Viral myc Genes and their Cellular Homologs. Chapter 8. Molecular Mechanisms Involved in Human B and T Cell Neoplasia. Chapter 9. Involvement of Oncogene-Coded Growth Factors in the Neoplastic Process. Chapter 10. Serum-Free Selection of Onc Genes. Chapter 11. The Role of Ionic Signals in Early Gene Induction During T Cell Activation. Chapter 12. Molecular Evolution of Ets Genes from Avians to Mammals and Their Cytogenetic Localization to Regions Involved in Leukemia. Chapter 13. Properties of the met Oncogene. Chapter 14. Oncogenes: Molecular Probes for Clinical Application in Malignant Diseases.

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