Metabolic control in diabetes mellitus, beta adrenoceptor blocking drugs, NMR analysis of cancer cells, immunoassay in the clinical laboratory, cyclosporine
著者
書誌事項
Metabolic control in diabetes mellitus, beta adrenoceptor blocking drugs, NMR analysis of cancer cells, immunoassay in the clinical laboratory, cyclosporine
（Progress in clinical biochemistry and medicine, 3）
Springer-Verlag, c1986
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注記
Includes bibliographies and index
収録内容
- Monitoring of metabolic control in diabetes mellitus : methodological and clinical aspects / R. Flückiger and W. Berger
- Recent chemical developments in the field of beta adrenoceptor blocking drugs / H.G. Köppe
- NMR analysis of cancer cells / C.E. Mountford, K.T. Holmes and I.C.P. Smith
- The role of immunoassay in the clinical laboratory / E.L. Nickoloff
- Cyclosporine : chemistry, structure-activity relationships and mode of action / R.M. Wenger, T.G. Payne and M.H. Schreier
内容説明・目次
内容説明
The close association between blood glucose control and the well-being of the patient, as well as the risk for the development of the "late" complications of 3 diabetes, make it necessary to attain near normalisation of blood glucosel- ). Signifi- cant progress has been made in this direction in the last few years because of the advancement of analytical techniques for the monitoring of both metabolic status and the functional state of the pancreas and the kidneys, organs involved in the disease process. The respective methodologies are the test strips for self-monitoring of glucose in blood and urine, the measurement of the nonenzymatic glycosylation of hemoglobin and serum proteins, the C-peptide assay, and the determination of small amounts of albumin in urine. The test strip methodology for determination of glucose in blood and urine has made possible home blood glucose monitoring which enables the patient to aim for treatment targets near the physiological range.
To this information on short term glycemia obtained by the patient, the determination of hemoglobin glycosylation in the clinical chemistry laboratory adds quantitative information about averaged long- term glycemic control. The C-peptide assay allows evaluation of the residual pancreatic function in the presence of exogenous insulin. Results of a C-peptide assay are helpful in selecting the appropriate treatment for poorly controlled maturity-onset diabetes. The detection of microalbuminuria, an abnormal albumin excretion below the level of "Albustix" detection, establishes nephropathy before renal damage becomes irreversible.
目次
Monitoring of Metabolic Control in Diabetes Mellitus: Methodological and Clinical Aspects.- Recent Chemical Developments in the Field of Beta Adrenoceptor Blocking Drugs.- NMR Analysis of Cancer Cells.- The Role of Immunoassay in the Clinical Laboratory.- Cyclosporine: Chemistry, Structure-Activity Relationships and Mode of Action.- Author Index Volumes 1-3.
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