Biological functions of proteinases : 30. Colloquium der Gesellschaft für Biologische Chemie, 26.-28. April 1979 in Mosbach/Baden
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Bibliographic Information
Biological functions of proteinases : 30. Colloquium der Gesellschaft für Biologische Chemie, 26.-28. April 1979 in Mosbach/Baden
Springer-Verlag, 1979
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- : gw
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Gesellschaft für Biologische Chemie
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Includes bibliographies and index
Description and Table of Contents
- Volume
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: us ISBN 9780387096834
Description
We are very pleased to introduce Open Source Development, Communities and Quality. The International Conference on Open Source Systems has come to its fourth edition - OSS 2008. Now, Free, Libre, and Open Source software is by all means now one of the most relevant subjects of study in several disciplines, ranging from information technology to social sciences and including also law, business, and political sciences. There are several conference tracks devoted to open source software with several publications appearing in high quality journals and magazines. OSS 2008 has been organized with the purpose of being the reference venue for those working in this area, being the most prominent conference in this area. For this th reason OSS 2008 has been located within the frameworks of the 20 World Computer Congress, WCC 2008, in Milan, the largest event of IFIP in 2008. We believe that this conference series, and the IFIP working group it represents, can play an important role in meeting these challenges, and hope that this book will become a valuable contribution to the open source body of research.
Table of Contents
Full Papers.- A Framework for Evaluating Managerial Styles in Open Source Projects.- Forging A Community - Not: Experiences On Establishing An Open Source Project.- Mapping Linux Security Targets to Existing Test Suites.- Overview on Trust in Large FLOSS Communities.- PMLite: An Open Source Solution for Process Monitoring.- Requirements Acquisition in Open Source Development: Firefox 2.0.- Analysis of Coordination Between Developers and Users in the Apache Community.- Lost and Gained in Translation: Adoption of Open Source Software Development at Hewlett-Packard.- Mining for Practices in Community Collections: Finds From Simple Wikipedia.- Open to Grok. How do Hackers' Practices Produce Hackers?.- Social Dynamics of FLOSS Team Communication Across Channels.- Towards a Global Research Infrastructure for Multidisciplinary Study of Free/Open Source Software Development.- Update Propagation Practices in Highly Reusable Open Source Components.- Using Social Network Analysis Techniques to Study Collaboration between a FLOSS Community and a Company.- Empirical Analysis of the Bug Fixing Process in Open Source Projects.- The Total Growth of Open Source.- Adoption of Open Source in the Software Industry.- Migration Discourse Structures: Escaping Microsoft's Desktop Path.- The SQO-OSS Quality Model: Measurement Based Open Source Software Evaluation.- Short Papers.- An Open Integrated Environment for Transparent Fuzzy Agents Design.- Archetypal Internet-Scale Source Code Searching.- Channeling Firefox Developers: Mom and Dad Aren't Happy Yet.- Continuous Integration in Open Source Software Development.- Extracting Generally Applicable Patterns from Object-Oriented Programs for the Purpose of Test Case Creation.- Social Networking Technologies for Free-Open Source E-Learning Systems.- The Networked Forge: New Environments for Libre Software Development.- To What Extent Does It Pay to Approach Open Source Software for a Big Telco Player?.- A Framework to Abstract The Design Practices of e-Learning System Projects.- Assessing Innovation in the Software Sector: Proprietary vs. FOSS Production Mode. Preliminary Evidence from the Italian Case.- Detecting Agility of Open Source Projects Through Developer Engagement.- Facilitating Social Network Studies of FLOSS using the OSSNetwork Environment.- Reflection on Knowledge Sharing in F/OSS Projects.- Usability in Company Open Source Software Context - Initial Findings from an Empirical Case Study.- Willingness to Cooperate Within the Open Source Software Domain.- Open Source Project Categorization Based on Growth Rate Analysis and Portfolio Planning Methods.- Applying Open Source Development Practices Inside a Company.- Towards The Evaluation of OSS Trustworthiness: Lessons Learned From The Observation of Relevant OSS Projects.- Open Source Reference Systems for Biometric Verification of Identity.- eResearch Workflows for Studying Free and Open Source Software Development.- Panels.- Panel: Opportunities and Risks for Open Source Software in Industry.- Posters and Demonstrations.- Open Source Environments for Collaborative Experiments in e-Science.
- Volume
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: gw ISBN 9783540096832
Description
Proteinases were among the first enzymes to be investigated biochemi- cally, and purification and crystallization especially of proteolytic enzymes of the digestive tract has contributed much to our present knowledge of enzymic structure and mechanisms of catalysis. However, for a long time little has been known about the functional aspects of proteinases. The only exception from this have been the digestive tract enzymes responsible for extracellular catalysis of protein breakdown and supply of amino acids for new-protein assembly and nitrogen metab- olism in the respective organs. The work of Schoenheimer, summarized for the first time in 1942 in a paper entitled "Dynamic state of body constituents", showed that continuous turnover of proteins takes place in cells. But scientists did not pay much attention to these findings at that time. The continuous accumulation of knowledge of a variety of intracellular proteolytic processes during the past decades has greatly stimulated research in this field. The central role of proteo- lysis in cellular regulation has become fully evident during recent years.
It is the aim of the 30th Mosbach Colloquium to present an over- view of our present knowledge of proteinase structure, function and control. The relationship between globular protein structure of a proteinase and induction of enzymic activity will be discussed for trypsin and trypsinogen activation. One significant proteinase action is the total degradation of proteins to serve cellular needs under different condi- tions.
Table of Contents
Conformational Flexibility and Its Functional Significance in Some Protein Molecules.- Intracellular Protein Turnover.- Studies of the Pathway for Protein Degradation in Escherichia coli and Mammalian Cells.- Lysosomes and Intracellular Proteolysis.- Genetic and Biochemical Analysis of Intracellular Proteolysis in Yeast.- Endogenous Inhibitors of Tissue Proteinases.- Activity of a Rat Uterus Proteinase Inhibitor During Pregnancy and Involution Its Possible Importance in Control of Proteolysis in the Myometrium.- Alkaline Proteinases in Skeletal Muscle.- Determinants in Protein Topology.- Import of Proteins into Mitochondria.- Localization and Some Properties of a Proteinase and a Carboxypeptidase from Rat Liver.- Processing of Bacteriophage Proteins.- Proteolysis, a Determinant for Virus Pathogenicity.- The Processing of Plasma Proteins in the Liver.- Protease Action in Carcinogenesis.- Plasminogen Activator from Cultured Cells and from Blood Plasma.- Role of Proteinases from Leukocytes in Inflammation.- Role of Granulocyte Elastase in Rheumatoid Arthritis: Effect on Mechanical Behaviour of Cartilage and Identification at the Cartilage/Pannus Junction.- Regulation of Proteinase Activity.- The Complement System.- Substrate Modulation as a Control Mechanism of Plasma Multienzyme Systems.- Blood Coagulation.- The Kallikrein-Kinin System: A Functional Role of Plasma Kallikrein and Kininogen in Blood Coagulation.- Hydrolysis of Peptide Bonds and Control of Blood Pressure.- Characterization of the Active Site of Angiotensin Converting Enzyme.- Proteolysis and Fertilization.
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