Neuropeptides and their peptidases
著者
書誌事項
Neuropeptides and their peptidases
（Ellis Horwood series in biomedicine）
VCH , Ellis Horwood, 1987
- : U.S
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注記
Includes bibliographies and index
内容説明・目次
内容説明
A selective review of neuropeptides that illustrate common aspects of the molecular biology, biosynthesis, processing, and metabolism of such peptides. The book moves from molecular biology through to the design of therapeutic agents. Among the topics discussed are the gene structures of a number of neuropeptide gene families, the expression of the oxytocin and vasopressin genes, and selected peptides of current interest, including tachykinins, gastric peptides, and atrial natriuretic peptides. Other topics considered are possible neurological deficits of neuropeptides and their peptidases and some of the enzymes that have been implicated in neuropeptide metabolism. The book also critically examines the status of the various neuropeptide processing enzymes and reviews the design and therapeutic applications of selective and potent inhibitors of zinc peptidases.
目次
- Part I_Molecular Biology of Neuropeptides
- Overview: Peptides in the Nervous System
- Neuropeptide Gene Families
- Vasopressinergic and Oxytocinergic Cells: Models in Neuropeptide Gene Expression
- Processing of Neuropeptide Precursors
- Part II_Selected Neuropeptides
- Mammalian Tachykinins: Neurochemistry and Pharmacology
- Gastrin, Cholecystokinin and Gastrin Releasing Peptide: Physiological Roles in the Alimentary Tract and the Brain
- Atrial Natriuretic Factor: Physiology and Biochemistry
- Neuropeptides and Their Peptidases in Neurological Illness
- Part III_Peptidases and Neuropeptide Metabolism
- Angiotensin I Converting Enzyme and its Role in Neuropeptide Metabolism
- Endopeptidase_24.11
- Calpains and Neuropeptide Metabolism
- Inhibition of Zinc Peptidases that Hydrolyse Neuropeptides
- Index.
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