Antibiotic inhibitors of bacterial cell wall biosynthesis
Author(s)
Bibliographic Information
Antibiotic inhibitors of bacterial cell wall biosynthesis
（International encyclopedia of pharmacology and therapeutics, section 127）
Pergamon Press, 1987
1st ed
- Uniform Title
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Pharmacology & therapeutics
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Note
"Published as Supplement no. 27 (1987) to the review journal Pharmacology and therapeutics"--T.p. verso
Includes bibliographies and index
Description and Table of Contents
Description
Since the advent of antibiotic drugs, epidemic bacterial infections have ceased to be a scourge on mankind. This volume presents an overview of the field of antibiotic action. It also includes descriptions of the major mechanisms of resistance that are increasingly becoming a serious problem in dealing with bacterial infections. In detailing the precise mechanisms of action and resistance, allied to the rational application of modern organic chemistry, this information should highlight better structures for classical antibiotics, as well as other areas of bacterial metabolism that may be sensitive to chemotherapy. In such a multidisciplinary field, this accumulation of knowledge should be invaluable to all those working on better antibiotics.
Table of Contents
- Biosynthesis of peptidoglycans, J. B. Ward. Inhibition of cell wall biosynthesis by analogues of alanine, F. C. Neuhaus & W. P. Ham
- es. Bacitracin, W. A. Toscano & D. R. Sto
- m. Vancomycin and related antibiotics, H. R. Perkins. Mode of action of beta-lactam antibiotics, D. J. Tipper. Modern beta-lactam antibiotics, R. B. Sykes et al. Role of permeability barriers in resistance to beta-lactam antibiotics, H. Nikaido. The role of beta-lactamase inhibitors in chemotherapy, H. C. Neu. Index.
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