The heritage of experimental embryology : Hans Spemann and the organizer

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The heritage of experimental embryology : Hans Spemann and the organizer

Viktor Hamburger

(Monographs on the history and philosophy of biology)

Oxford University Press, 1988

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Note

Bibliography: p. 181-189

Includes index

Description and Table of Contents

Description

Experimental embryology, which was founded in the 1880's and came of age in the first decades of this century, became the foundation for modern cellular and developmental biology. One of the embryology's uncontested leaders was the German biologist Hans Spemann. Professor Hamburger presents a critical account of Spemann's Nobel Prize in 1935. The author traces the different lines of research which emerged from Spemann's seminal discovery and carries the history up to the 1950's when classical embryology was superseded by molecular-developmental biology. Hamburger is uniquely qualified to write this volume: he spent almost a decade in Spemann's laboratory, first as a graduate student, and later as research colleague. As a mature and distinguished scientist working in the United States, Hamburger played a crucial role in establishing the field of developmental neurobiology.

Table of Contents

  • Introduction
  • History of the Organizer Experiment
  • The Organizer Experiment (1924)
  • Further Explorations of the Organizer and of Induction (1925-1931)
  • The Mechanisms of Induction - The Turning Point
  • New Approaches to problems of Determination and Induction - The Ascendance of J. Holtfreter (1931-1940)
  • In-Vitro Isolation Experiments (1938, 1965)
  • The Fusion of Biochemistry and Entwicklungsmechanik
  • Regional Induction - Specificity of Heterogenenous Inductors.

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