Asthma : clinical pharmacology and therapeutic progress

著者

書誌事項

Asthma : clinical pharmacology and therapeutic progress

edited by A.B. Kay

Blackwell Scientific Publications , Blackwell Mosby [distributor], 1986

大学図書館所蔵 件 / 全5件

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注記

Papers first presented to a course sponsored by the Cardiothoracic Institute, London and held Nov. 1984

Includes bibliographies and index

内容説明・目次

内容説明

This book aims to be an up-to-date and authoritative account by leading experts of developments in our understanding of the pathophysiology of asthma and the implications for treatment. The special feature of the book is the way in which new approaches to the treatment of asthma are put on a scientific basis.

目次

  • Mediators and inflammatory cells in asthma
  • Allergen-induced late bronchial responses: physiologic and pharmacologic responses in the allergic sheep
  • Experimental models of bronchial asthma in man and the rabbit
  • Inflammatory cells and mediators in allergen-induced late-phase asthmatic reactions
  • Bronchoalveolar lavage and the late asthmatic reaction
  • Neuropeptides in the airways: functional significance
  • The localization of neuropeptides in the mammalian respiratory tract
  • The role of vasoactive intestinal peptide (VIR) in asthma
  • Airways smooth muscle: an overview of morphology, electrophysiology and aspects of the pharmacology of contraction and relaxation
  • Calcium ions and contraction of airways smooth muscle
  • Calcium antagonists and airways smooth muscle
  • Bronchodilator mechanisms
  • Clinical applications of beta-agonists
  • Beta-agonists as mast cell stabilizers
  • Biological properties of lipoxygenase products: an overview
  • Leukotrienes and asthma
  • Leukotrienes and the upper airways
  • The synthesis, release and effects of prostaglandins in the lung
  • Platelets and aspirin-induced asthma
  • PAF-acemer (platelet activating factor): an update
  • Mast cell heterogeneity: an overview
  • Nedocromil sodium (Tilade): a selective mucosal mast cell stabilizer
  • Human bronchoalveolar mast cells and their mediators
  • Histochemical aspects of the staining of mast cells with particular reference to heterogeneity and quantification
  • Histamine release from human lung mast cells
  • Glucocorticoid-resistant asthma: evidence for a defect in mononuclear cells
  • Modes of administration of corticosteroids
  • Inhibition by inhaled corticosteroid of bronchoconstriciton induced by allergen and exercise challenge tests
  • Corticosteroids and leucocyte activation in chronic asthma
  • Clinical patterns of responsiveness to corticosteroids
  • Respiratory lining fluid
  • Innervation of airway epithelium
  • Heat loss, osmolarity and the respiratory epithelium.

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