Drug metabolism : molecular approaches and pharmacological implications : proceedings of the 9th European Workshop on Drug Metabolism held at Pont-à-Mousson, 11-15 June 1984
著者
書誌事項
Drug metabolism : molecular approaches and pharmacological implications : proceedings of the 9th European Workshop on Drug Metabolism held at Pont-à-Mousson, 11-15 June 1984
Pergamon Press, c1985
- 統一タイトル
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Biochemical pharmacology
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注記
"Published as supplement no. 1, 1985 to the journal Biochemical pharmacology"--T.p. verso
Includes bibliographies
内容説明・目次
内容説明
This volume reviews some of the latest advances in the investigation of drug metabolism. In particular, coverage of the increasing contributions to the field of current techniques in molecular biology and biotechnology is given.
目次
(partial) Assessment of drug metabolising enzyme activity in man, B K Park. Human hepatocyte cultures in the assessment of drug metabolism in man, A Guillouzo et al. Free radical intermediates in relation to tissue injury, K Cheeseman et al. Carbon radicals as metabolic intermediates, P R Ortiz de Montellano. Effects of macrolide antibiotics on cytochromes P-450 in rats and humans, D Pessayre. Antibody methods for monitoring carcinogen exposure, R C Garner. Biotransformation in non-microsomal compartments, E Bresnick. Fast atom bombardment and thermospray mass spectrometry, C Fenselau & B S Larsen. Microbial models of mammalian metabolism, R V Smith. Production of natural compounds by plant tissue and cell cultures: problems and perspectives, V Petiard. Lipophilicity and drug metabolism: qualitative and quantitative relationships, J M Mayer. Particular ability of cytochromes P-450 to form reactive intermediates and metabolites, D Mansuy & P Battioni. Detection and importance of excited species in biological reactions, E Cadenas. Lipid hydroperoxide-dependent xenobiotic metabolism, L J Marnett et al.
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