Iron and infection : molecular, physiological and clinical aspects

著者

書誌事項

Iron and infection : molecular, physiological and clinical aspects

edited by J.J. Bullen and E. Griffiths

Wiley, c1987

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注記

"A Wiley Interscience publication."

Includes index

内容説明・目次

内容説明

Interest in the relationship between iron and infection has increased enormously in recent years and the topic has become a very active area of research. Although several short review articles have appeared in the literature, up to now, there has been no comprehensive book giving an integrated account of the role of iron in microbial pathogenicity and in clinical infection. This book presents the most relevant new advances in the biochemistry, microbiology, molecular genetics and clinical science of the subject in depth, and highlights the gaps in our knowledge. The work encompasses bacterial, fungal and protozoal pathogens and also discusses recent discoveries which show the importance of iron uptake mechanisms to malignant and other rapidly proliferating cells. The significance of recent developments for the design and use of new vaccines and for therapeutic measures used in treating infections are also considered. The book will thus be of interest to medical microbiologists interested in infectious diseases, immunologists, microbial geneticists, haematologists and biochemists.

目次

  • Iron in Biological Systems
  • Iron Proteins
  • The Iron Uptake Systems of Pathogenic Bacteria
  • Bacterial Iron Metabolism, Plasmids and other Virulent Factors
  • Iron-Binding Proteins and Host Defence
  • Iron and the Antibacterial Function of Polymorphonuclear Leucocytes
  • Clinical and Physiological Aspects
  • Future Prospects.

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