Clinical radiobiology

著者

    • Nias, A. H. W.
    • Duncan, William

書誌事項

Clinical radiobiology

A.H.W. Nias

Churchill Livingstone, 1988

2nd ed

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注記

Duncan's name appears first on the earlier edition

Includes bibliographies and index

内容説明・目次

内容説明

The clinical applications of radiobiology to the treatment of cancer patients by radiotherapy are examined in this text, which stresses the use of applied radiobiology and its relevance to clinical practice. The basic science of radiobiology is introduced with particular attention to mammalian cells and tissues. Some of the effects of anti-cancer drugs are discussed, particularly when such drugs are used in combination with radiation. Quantitative assays of radiation are described together with the mathematical formulae used to relate the various drug responses. The contrast between early and late reactions to radiation is explained, with particular emphasis upon the results of the different fractionation schedules used in clinical radiotherapy. The radiobiological basis of new forms of radiotherapy is also described and advice is offered on the most effective use of these new regimes. Finally, the long-term hazards of radiation to both radiation workers and the general public are described, stating the risks and safety levels. The work is recommended reading for those taking FRCRad Part 1 examinations.

目次

  • Biophysical events
  • the biological target
  • biochemical damage
  • cell survival curves
  • modification of cell survival
  • recovery from cytotoxic damage
  • early response of normal tisues
  • total body syndromes
  • response of tumours
  • late effects on normal tissues
  • fractionation
  • clinical applications
  • experimental therapy
  • risks and safety.

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詳細情報

  • NII書誌ID(NCID)
    BA06772531
  • ISBN
    • 0443033404
  • LCCN
    88005049
  • 出版国コード
    uk
  • タイトル言語コード
    eng
  • 本文言語コード
    eng
  • 出版地
    Edinburgh ; New York
  • ページ数/冊数
    279 p.
  • 大きさ
    25 cm
  • 分類
  • 件名
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