Toxic susceptibility : male/female differences
著者
書誌事項
Toxic susceptibility : male/female differences
（Environmental science and technology）
Wiley, c1985
- est.
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注記
"A Wiley-Interscience publication."
Includes bibliographies and index
内容説明・目次
内容説明
A critical assessment of the animal models of human clinical and population-based studies that highlight the physiological and biochemical differences between male-female responses to toxic substances. Focuses on the organ systems that are especially sensitive to toxicants and pollutants. Investigates the extent to which the pregnant state may alter a susceptibility to toxic substances, with particular emphasis on alterations in drug metabolism. Shows the significance such findings have for regulatory agencies concerned with environmental health.
目次
Partial table of contents: SEX DIFFERENCES IN BIOCHEMICAL/PHYSIOLOGICAL PROCESSES. Absorption: Gastrointestinal Tract. Plasma Protein Binding. PREGNANCY. Physiological Changes. Protein Binding. Drug Metabolism. SEX DIFFERENCES TO LIVER TOXINS. Ethionine. Orotic Acid. Carbon Tetrachloride. SEX DIFFERENCES TO RENAL TOXINS. Structural/Functional Differences Between Male and Female Rat Kidney. Petroleum. INORGANIC CONTAMINANTS. Ammonia. Cadmium. Chromium. ORGANIC CONTAMINANTS. Pesticides. Mycotoxins. DRUGS. Ethyl Alcohol. Narcotic Analgesics. Barbiturates. Mild Analgesics. Anticonvulsants. CNS Stimulants. Lithium. Diazepines. Local Anesthetics. ORAL CONTRACEPTIVES. Drug Metabolism. Carbon Disulfide. ENDOGENOUS AND RELATED SUBSTANCES. Vitamin C. Testosterone. SUMMARY. Sex Differences and Animal Extrapolation. Sex Differences in Humans. Safety Factors. Index.
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